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Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Cash flows from operating activities:
Net loss	$ (4,365)	$ (4,984)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation	547	147
Depreciation and amortization	17	87
Accretion on marketable securities	82	82
Changes in operating assets and liabilities:
Prepaid and other current assets	(223)	(3)
Other assets	91	90
Accounts payable, accrued liabilities and other liabilities	(1,635)	(1,718)
Net cash used in operating activities	(5,486)	(6,299)
Cash flows from investing activities:
Purchase of marketable securities	(16,264)	(24,144)
Sale of marketable securities	25,005	22,964
Acquisition of property and equipment	0	(9)
Net cash provided by (used in) investing activities	8,741	(1,189)
Cash flows from financing activities:
Proceeds from exercise of options	0	40
Tax withholding payments on net share settlement equity awards	(130)	(45)
Net proceeds from issuance of common stock	1,000	0
Repayment of notes payable	0	(67)
Net cash provided by (used in) financing activities	870	(72)
Net increase (decrease) in cash, cash equivalents and restricted cash	4,125	(7,560)
Cash, cash equivalents and restricted cash at beginning of period	10,299	34,168
Cash, cash equivalents and restricted cash at end of period	14,424	26,608
Cash paid during the period for:
Interest	$ 0	$ 3

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