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Stockholders' Equity - Equity Issuances (Details) - USD ($) |  | 1 Months Ended | 12 Months Ended | 35 Months Ended |
--- | --- | --- | --- | --- | ---
Jul. 10, 2020 | May 31, 2020 | Apr. 30, 2020 | Mar. 31, 2019 | Aug. 31, 2018 | Dec. 31, 2020 | Dec. 31, 2020 | Feb. 28, 2018
Lincoln Park Agreement |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Aggregate offering amount authorized per agreement |  |  |  | $ 26,000,000.0 |  |  |  |
Commitment shares issued as consideration per agreement (shares) |  |  |  | 181,510 |  |  |  |
Number of shares sold (shares) |  |  |  | 250,000 |  |  |  |
Price of shares sold (in dollars per share) |  |  |  | $ 4.00 |  |  |  |
Gross price for stock transaction |  |  |  | $ 1,000,000 |  |  |  |
Term of agreement (in months) |  |  |  | 36 months |  |  |  |
Number of shares allowable to direct for Regular Purchase (shares) |  |  |  | 100,000 |  |  |  |
Maximum obligation per directed purchase transaction for Regular Purchase |  |  |  | $ 2,500,000 |  |  |  |
Maximum shares allowed in Accelerated Purchase as percent of shares in Regular Purchase (percent) |  |  |  | 300.00% |  |  |  |
Maximum shares allowed in Accelerated Purchase as percent of shares traded during specified period (percent) |  |  |  | 30.00% |  |  |  |
Maximum beneficial ownership allowable per agreement (percent) |  |  |  | 9.99% |  |  |  |
H.C. Wainwright Sales Amended Agreement |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Aggregate offering amount authorized per agreement |  |  |  | $ 17,600,000 | $ 25,000,000.0 |  |  | $ 25,000,000.0
Aggregate market value of common stock held by non-affiliates |  |  |  | $ 52,800,000 |  |  |  |
Maximum number of shares authorized per agreement (shares) |  |  |  | 4,800,000 |  |  |  |
Commission on gross proceeds due to third party (percent) |  |  |  |  | 3.00% |  |  |
Stock issued (shares) |  |  |  |  |  | 3,558,778 | 3,784,912 |
Proceeds from issuance of stock |  |  |  |  |  | $ 8,500,000 | $ 9,500,000 |
April Purchase Agreement |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Number of shares sold (shares) |  |  | 2,162,166 |  |  |  |  |
Price of shares sold (in dollars per share) |  |  | $ 2.3125 |  |  |  |  |
Number of shares called by warrants issued |  |  | 1,081,083 |  |  |  |  |
Proceeds from issuance of stock |  |  | $ 5,000,000.0 |  |  |  |  |
Number of shares per each warrant |  |  | 1 |  |  |  |  |
Warrant exercise price (in dollars per share) |  |  | $ 2.2500 |  |  |  |  |
Warrants expiration term |  |  | 5 years 6 months |  |  |  |  |
May Purchase Agreement |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Number of shares sold (shares) |  | 2,084,850 |  |  |  |  |  |
Price of shares sold (in dollars per share) |  | $ 2.0625 |  |  |  |  |  |
Number of shares called by warrants issued |  | 1,042,425 |  |  |  |  |  |
Proceeds from issuance of stock |  | $ 4,300,000 |  |  |  |  |  |
Number of shares per each warrant |  | 1 |  |  |  |  |  |
Warrant exercise price (in dollars per share) |  | $ 2.0625 |  |  |  |  |  |
Warrants expiration term |  | 5 years 6 months |  |  |  |  |  |
July 2020 Private Placement |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |
Number of shares sold (shares) | 969,694 |  |  |  |  |  |  |
Price of shares sold (in dollars per share) | $ 2.0625 |  |  |  |  |  |  |
Number of shares called by warrants issued | 484,847 |  |  |  |  |  |  |
Proceeds from issuance of stock | $ 2,000,000.0 |  |  |  |  |  |  |
Number of shares per each warrant | 1 |  |  |  |  |  |  |
Warrant exercise price (in dollars per share) | $ 2.0625 |  |  |  |  |  |  |
Warrants expiration term | 5 years 6 months |  |  |  |  |  |  |

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