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Share-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2021
Share-based Payment Arrangement, Noncash Expense [Abstract]  
Schedule Share-based Compensation Expense The following table summarizes the components of share-based compensation expense for the three and six months ended June 30, 2021 and 2020 (in thousands):
Three Months Ended June 30,Six Months Ended June 30,
2021202020212020
Research and development$24 $56 $120 $181 
General and administrative246 239 747 680 
Total share-based compensation expense$270 $295 $867 $861 
Schedule of Total Compensation Cost Related to Nonvested Awards
Total compensation cost related to non-vested awards not yet recognized and the weighted-average periods over which the awards were expected to be recognized at June 30, 2021 were as follows (in thousands):
Stock OptionsRestricted Stock UnitsRestricted Stock
Unrecognized compensation cost$338 $407 $493 
Expected weighted-average period in years of compensation cost to be recognized1.731.262.01
Schedule of Fair Value of Share-based Compensation Awards
Total fair value of shares vested and the weighted average estimated fair values of shares granted for the six months ended June 30, 2021 and 2020 were as follows (in thousands):
Stock Options
Six Months Ended June 30,
20212020
Total fair value of shares vested$407 $515 
Weighted average estimated fair value of shares granted$1.08 $2.12