    <SEC-DOCUMENT>0000320017-21-000075-index.html : 20210604
    <SEC-HEADER>0000320017-21-000075.hdr.sgml : 20210604
    <ACCEPTANCE-DATETIME>20210604164411
    ACCESSION NUMBER:		0000320017-21-000075
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		46
    CONFORMED PERIOD OF REPORT:	20210604
    ITEM INFORMATION:		Entry into a Material Definitive Agreement
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20210604
    DATE AS OF CHANGE:		20210604

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			CALADRIUS BIOSCIENCES, INC.
    		CENTRAL INDEX KEY:			0000320017
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
    		IRS NUMBER:				222343568
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33650
    		FILM NUMBER:		21997055

    	BUSINESS ADDRESS:
    		STREET 1:		110 ALLEN ROAD
    		STREET 2:		SECOND FLOOR
    		CITY:			BASKING RIDGE
    		STATE:			NJ
    		ZIP:			07920
    		BUSINESS PHONE:		908-842-0100

    	MAIL ADDRESS:
    		STREET 1:		110 ALLEN ROAD
    		STREET 2:		SECOND FLOOR
    		CITY:			BASKING RIDGE
    		STATE:			NJ
    		ZIP:			07920

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Caladrius Biosciences, Inc.
    		DATE OF NAME CHANGE:	20150608

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NeoStem, Inc.
    		DATE OF NAME CHANGE:	20060906

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	PHASE III MEDICAL INC/DE
    		DATE OF NAME CHANGE:	20030819
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>a8-kjune2021salesagm.htm
    <DESCRIPTION>8-K
    <TEXT>
    Document 1 - file: a8-kjune2021salesagm.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-5.1
    <SEQUENCE>2
    <FILENAME>ex51tosalesagm20210604.htm
    <DESCRIPTION>EX-5.1
    <TEXT>
    Document 2 - file: ex51tosalesagm20210604.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.1
    <SEQUENCE>3
    <FILENAME>exhibit101atmagreementju.htm
    <DESCRIPTION>EX-10.1
    <TEXT>
    Document 3 - file: exhibit101atmagreementju.htm

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    <SEQUENCE>4
    <FILENAME>exhibit101atmagreementju001.jpg
    <DESCRIPTION>GRAPHIC
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    Document 4 - file: exhibit101atmagreementju001.jpg

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    <DOCUMENT>
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    <SEQUENCE>5
    <FILENAME>exhibit101atmagreementju002.jpg
    <DESCRIPTION>GRAPHIC
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    Document 5 - file: exhibit101atmagreementju002.jpg

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    <SEQUENCE>6
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    Document 6 - file: exhibit101atmagreementju003.jpg

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    Document 7 - file: exhibit101atmagreementju004.jpg

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    Document 8 - file: exhibit101atmagreementju005.jpg

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    <DOCUMENT>
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    <FILENAME>exhibit101atmagreementju006.jpg
    <DESCRIPTION>GRAPHIC
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    Document 9 - file: exhibit101atmagreementju006.jpg

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    <SEQUENCE>10
    <FILENAME>exhibit101atmagreementju007.jpg
    <DESCRIPTION>GRAPHIC
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    Document 10 - file: exhibit101atmagreementju007.jpg

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    <SEQUENCE>11
    <FILENAME>exhibit101atmagreementju008.jpg
    <DESCRIPTION>GRAPHIC
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    Document 11 - file: exhibit101atmagreementju008.jpg

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    Document 12 - file: exhibit101atmagreementju009.jpg

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    Document 13 - file: exhibit101atmagreementju010.jpg

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    <SEQUENCE>14
    <FILENAME>exhibit101atmagreementju011.jpg
    <DESCRIPTION>GRAPHIC
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    Document 14 - file: exhibit101atmagreementju011.jpg

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    <SEQUENCE>15
    <FILENAME>exhibit101atmagreementju012.jpg
    <DESCRIPTION>GRAPHIC
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    Document 15 - file: exhibit101atmagreementju012.jpg

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    <SEQUENCE>16
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    <DESCRIPTION>GRAPHIC
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    Document 16 - file: exhibit101atmagreementju013.jpg

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    <SEQUENCE>17
    <FILENAME>exhibit101atmagreementju014.jpg
    <DESCRIPTION>GRAPHIC
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    Document 17 - file: exhibit101atmagreementju014.jpg

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    <SEQUENCE>18
    <FILENAME>exhibit101atmagreementju015.jpg
    <DESCRIPTION>GRAPHIC
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    Document 18 - file: exhibit101atmagreementju015.jpg

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    <SEQUENCE>19
    <FILENAME>exhibit101atmagreementju016.jpg
    <DESCRIPTION>GRAPHIC
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    Document 19 - file: exhibit101atmagreementju016.jpg

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    <SEQUENCE>20
    <FILENAME>exhibit101atmagreementju017.jpg
    <DESCRIPTION>GRAPHIC
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    Document 20 - file: exhibit101atmagreementju017.jpg

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    <SEQUENCE>21
    <FILENAME>exhibit101atmagreementju018.jpg
    <DESCRIPTION>GRAPHIC
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    Document 21 - file: exhibit101atmagreementju018.jpg

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    <SEQUENCE>22
    <FILENAME>exhibit101atmagreementju019.jpg
    <DESCRIPTION>GRAPHIC
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    Document 22 - file: exhibit101atmagreementju019.jpg

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    <SEQUENCE>23
    <FILENAME>exhibit101atmagreementju020.jpg
    <DESCRIPTION>GRAPHIC
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    Document 23 - file: exhibit101atmagreementju020.jpg

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    <SEQUENCE>24
    <FILENAME>exhibit101atmagreementju021.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: exhibit101atmagreementju021.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>exhibit101atmagreementju022.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: exhibit101atmagreementju022.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>exhibit101atmagreementju023.jpg
    <DESCRIPTION>GRAPHIC
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    Document 26 - file: exhibit101atmagreementju023.jpg

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    <DOCUMENT>
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    <SEQUENCE>27
    <FILENAME>exhibit101atmagreementju024.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: exhibit101atmagreementju024.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>exhibit101atmagreementju025.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: exhibit101atmagreementju025.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>exhibit101atmagreementju026.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: exhibit101atmagreementju026.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>exhibit101atmagreementju027.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 30 - file: exhibit101atmagreementju027.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>exhibit101atmagreementju028.jpg
    <DESCRIPTION>GRAPHIC
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    Document 31 - file: exhibit101atmagreementju028.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>exhibit101atmagreementju029.jpg
    <DESCRIPTION>GRAPHIC
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    Document 32 - file: exhibit101atmagreementju029.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>exhibit101atmagreementju030.jpg
    <DESCRIPTION>GRAPHIC
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    Document 33 - file: exhibit101atmagreementju030.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>exhibit101atmagreementju031.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 34 - file: exhibit101atmagreementju031.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>exhibit101atmagreementju032.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 35 - file: exhibit101atmagreementju032.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>exhibit101atmagreementju033.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 36 - file: exhibit101atmagreementju033.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>exhibit101atmagreementju034.jpg
    <DESCRIPTION>GRAPHIC
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    Document 37 - file: exhibit101atmagreementju034.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>38
    <FILENAME>exhibit101atmagreementju035.jpg
    <DESCRIPTION>GRAPHIC
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    Document 38 - file: exhibit101atmagreementju035.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>39
    <FILENAME>exhibit101atmagreementju036.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 39 - file: exhibit101atmagreementju036.jpg

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    <SEQUENCE>40
    <FILENAME>exhibit101atmagreementju037.jpg
    <DESCRIPTION>GRAPHIC
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    Document 40 - file: exhibit101atmagreementju037.jpg

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    <SEQUENCE>41
    <FILENAME>exhibit101atmagreementju038.jpg
    <DESCRIPTION>GRAPHIC
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    Document 41 - file: exhibit101atmagreementju038.jpg

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    <SEQUENCE>42
    <FILENAME>exhibit101atmagreementju039.jpg
    <DESCRIPTION>GRAPHIC
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    Document 42 - file: exhibit101atmagreementju039.jpg

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    <SEQUENCE>43
    <FILENAME>exhibit101atmagreementju040.jpg
    <DESCRIPTION>GRAPHIC
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    Document 43 - file: exhibit101atmagreementju040.jpg

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    <SEQUENCE>44
    <FILENAME>exhibit101atmagreementju041.jpg
    <DESCRIPTION>GRAPHIC
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    Document 44 - file: exhibit101atmagreementju041.jpg

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    <FILENAME>exhibit101atmagreementju042.jpg
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    Document 45 - file: exhibit101atmagreementju042.jpg

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    <TYPE>GRAPHIC
    <SEQUENCE>46
    <FILENAME>mintz.jpg
    <TEXT>
    Document 46 - file: mintz.jpg

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