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    CONFORMED SUBMISSION TYPE:	10-K/A
    PUBLIC DOCUMENT COUNT:		40
    CONFORMED PERIOD OF REPORT:	20211231
    FILED AS OF DATE:		20220421
    DATE AS OF CHANGE:		20220421

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			CALADRIUS BIOSCIENCES, INC.
    		CENTRAL INDEX KEY:			0000320017
    		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
    		IRS NUMBER:				222343568
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		10-K/A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33650
    		FILM NUMBER:		22841429

    	BUSINESS ADDRESS:
    		STREET 1:		110 ALLEN ROAD
    		STREET 2:		SECOND FLOOR
    		CITY:			BASKING RIDGE
    		STATE:			NJ
    		ZIP:			07920
    		BUSINESS PHONE:		908-229-2590

    	MAIL ADDRESS:
    		STREET 1:		110 ALLEN ROAD
    		STREET 2:		SECOND FLOOR
    		CITY:			BASKING RIDGE
    		STATE:			NJ
    		ZIP:			07920

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Caladrius Biosciences, Inc.
    		DATE OF NAME CHANGE:	20150608

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NeoStem, Inc.
    		DATE OF NAME CHANGE:	20060906

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	PHASE III MEDICAL INC/DE
    		DATE OF NAME CHANGE:	20030819
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