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Stockholders' Equity - Stock Options and Warrants (Details) - USD ($) $ / shares in Units, $ in Thousands | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2022 | Dec. 31, 2021
Stock Options, Shares |  |
Options, Outstanding, Beginning of Period (in shares) | 142,041 |
Options, Granted (in shares) | 37,458 |
Options, Exercised (in shares) | 0 |
Options, Forfeited (in shares) | (2,910) |
Options, Expired (in shares) | (5,388) |
Options, Outstanding, End of Period (in shares) | 1,398,977 | 142,041
Options, Vested and expected to vest (in shares) | 1,396,921 |
Options, Vested (in shares) | 1,110,635 |
Stock Options, Weighted Average Exercise Price |  |
Options, Outstanding. Beginning of Period (in dollars per share) | $ 84.60 |
Options, Granted (in dollars per share) | 13.49 |
Options, Exercised (in dollars per share) | 0 |
Options, Forfeited (in dollars per share) | 19.96 |
Options, Expired (in dollars per share) | 352.31 |
Options, Outstanding, End of Period (in dollars per share) | 10.83 | $ 84.60
Options, Vested and expected to vest (in dollars per share) | 10.83 |
Options, Vested (in dollars per share) | $ 11.82 |
Stock Options, Weighted Average Contractual Term and Intrinsic Value |  |
Options, Outstanding, Weighted Average Remaining Contractual Term | 7 years 3 months 18 days | 7 years 11 months 19 days
Options, Vested and expected to vest, Weighted Average Remaining Contractual Term | 7 years 3 months 18 days |
Options, Vested, Weighted Average Remaining Contractual Term | 6 years 11 months 19 days |
Options, Outstanding, Aggregate Intrinsic Value | $ 0 | $ 0
Options, Vested and expected to vest, Aggregate Intrinsic Value | 0 |
Options, Vested, Aggregate Intrinsic Value | $ 0 |
Warrants, Shares |  |
Warrants, Outstanding, Beginning of Period (in shares) | 1,423,774 |
Warrants, Granted (in shares) | 0 |
Warrants, Exercised (in shares) | 0 |
Warrants, Forfeited (in shares) | 0 |
Warrants, Expired (in shares) | 0 |
Warrants, Outstanding, End of Period (in shares) | 1,423,774 | 1,423,774
Warrants, Vested and expected to vest (in shares) | 1,423,774 |
Warrants, Vested (in shares) | 1,423,774 |
Warrants, Weighted Average Exercise Price |  |
Warrants Outstanding, Beginning of Period (in dollars per share) | $ 42.57 |
Warrants, Granted (in dollars per share) | 0 |
Warrants, Exercised (in dollars per share) | 0 |
Warrants, Forfeited (in dollars per share) | 0 |
Warrants, Expired (in dollars per share) | 0 |
Warrants Outstanding, End of Period (in dollars per share) | 42.57 | $ 42.57
Weighted Average Exercise Price, Warrants Vested And Expected To Vest | 42.57 |
Warrants, Vested, Weighted Average Exercise Price (in dollars per share) | $ 42.57 |
Warrants, Weighted Average Contractual Term and Intrinsic Value |  |
Warrants, Outstanding, Weighted Average Remaining Contractual Term | 3 years 7 months 17 days | 4 years 4 months 13 days
Warrants, Vested and expected to vest, Weighted Average Remaining Contractual Term | 3 years 7 months 17 days |
Warrants, Vested, Weighted Average Remaining Contractual Term | 3 years 7 months 17 days |
Warrants Outstanding, Aggregate Intrinsic Value | $ 0 | $ 0
Warrants, Vested and expected to vest, Aggregate Intrinsic Value | 0 |
Warrants, Vested, Aggregate Intrinsic Value | $ 0 |

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