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License Agreements (Details) - USD ($) | Dec. 31, 2021 | Oct. 31, 2021 | Mar. 31, 2021 | Dec. 31, 2015
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Annual license maintenance fee, after first sale |  | $ 150,000,000 |  |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Shares issued under license agreement |  |  |  | 382,030
Annual license maintenance fee |  | 20,000,000 |  | $ 10,000,000
Annual license maintenance fee, year seven |  |  |  | 20,000,000
Potential milestone payments |  | $ 23,200,000 |  | $ 10,600,000
Royalties, net of sales |  | 4.00% |  | 4.00%
Sublicensing fee |  |  |  | $ 0.25
Annual license maintenance fee, year four |  | $ 30,000,000 |  |
Shares held by third party | 382,030 |  |  |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  | 0.10 |  |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  | 0.25 |  |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Potential milestone payments |  |  | $ 1,200,000 |
Royalties, net of sales |  |  | 1.50% |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  |  | $ 0.10 |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  |  | $ 0.20 |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Annual license maintenance fee |  | 20,000,000 |  |
Potential milestone payments |  | $ 5,000,000 |  |
Royalties, net of sales |  | 2.00% |  |
Annual license maintenance fee, year four |  | $ 50,000,000 |  |
Annual license maintenance fee, years two and three |  | 25,000,000 |  |
Change of control fee |  | 300,000 |  |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  | 0.03 |  |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |
Sublicensing fee |  | $ 0.20 |  |

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- Definition Collaborative Arrangement, Rights and Obligations, Annual License Maintenance Fee + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Annual License Maintenance Fee After First Sale + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Annual License Maintenance Fee Starting at Year Seven + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Annual License Maintenance Fee Year Four + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Annual License Maintenance Fee Year Two and Three + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Change of Control Fee + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Maximum Aggregate Milestone Payments, Per Product + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Royalties Net of Sales + References No definition available. + Details
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- Definition Collaborative Arrangement, Rights and Obligations, Sublicensing Fees + References No definition available. + Details
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- Definition Shares Held by Third Party + References No definition available. + Details
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- Definition Shares Issued Under License Agreement + References No definition available. + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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