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Share-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2022
Share-based Payment Arrangement, Noncash Expense [Abstract]  
Schedule Share-based Compensation Expense The following table summarizes the components of share-based compensation expense for the three and nine months ended September 30, 2022 and 2021 (in thousands):
Three Months Ended September 30,Nine Months Ended September 30,
2022202120222021
Research and development$271 $523 $631 $643 
General and administrative769 250 1,537 996 
Total share-based compensation expense$1,040 $773 $2,168 $1,639 
Schedule of Total Compensation Cost Related to Nonvested Awards
Total compensation cost related to non-vested awards not yet recognized and the weighted-average periods over which the awards were expected to be recognized at September 30, 2022 were as follows (in thousands):
Stock OptionsRestricted Stock UnitsRestricted Stock
Unrecognized compensation cost$1,577 $168 $722 
Expected weighted-average period in years of compensation cost to be recognized1.662.161.83
Schedule of Fair Value of Share-based Compensation Awards
Total fair value of shares vested and the weighted average estimated fair values of shares granted for the nine months ended September 30, 2022 and 2021 were as follows (in thousands):
Stock Options
Nine Months Ended September 30,
20222021
Total fair value of shares vested$853 $757 
Weighted average estimated fair value of shares granted$1.23 $13.59