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Stockholders' Equity - Stock Options and Warrants (Details) - USD ($)
 3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
Stock Options, Shares    
Options, Outstanding, Beginning of Period (in shares) 1,391,352  
Options, Granted (in shares) 103,850  
Options, Exercised (in shares) 0 (1,227,776)
Options, Forfeited (in shares) 0  
Options, Expired (in shares) (2,520)  
Options, Outstanding, End of Period (in shares) 1,492,682 1,391,352
Options, Vested and expected to vest (in shares) 1,486,393  
Options, Vested (in shares) 1,207,228  
Stock Options, Weighted Average Exercise Price    
Options, Outstanding. Beginning of Period (in dollars per share) $ 10.83  
Options, Granted (in dollars per share) 3.11  
Options, Exercised (in dollars per share) 0  
Options, Forfeited (in dollars per share) 0  
Options, Expired (in dollars per share) 224.37  
Options, Outstanding, End of Period (in dollars per share) 9.94 $ 10.83
Options, Vested and expected to vest (in dollars per share) 9.96  
Options, Vested (in dollars per share) $ 10.90  
Stock Options, Weighted Average Contractual Term and Intrinsic Value    
Options, Outstanding, Weighted Average Remaining Contractual Term 7 years 3 days 7 years 10 days
Options, Vested and expected to vest, Weighted Average Remaining Contractual Term 7 years  
Options, Vested, Weighted Average Remaining Contractual Term 6 years 7 months 20 days  
Options, Outstanding, Aggregate Intrinsic Value $ 359,400 $ 187,600
Options, Vested and expected to vest, Aggregate Intrinsic Value 358,200  
Options, Vested, Aggregate Intrinsic Value $ 344,400  
Warrants, Shares    
Warrants, Outstanding, Beginning of Period (in shares) 1,423,774  
Warrants, Granted (in shares) 0  
Warrants, Exercised (in shares) 0  
Warrants, Forfeited (in shares) 0  
Warrants, Expired (in shares) 0  
Warrants, Outstanding, End of Period (in shares) 1,423,774 1,423,774
Warrants, Vested and expected to vest (in shares) 1,423,774  
Warrants, Vested (in shares) 1,423,774  
Warrants, Weighted Average Exercise Price    
Warrants Outstanding, Beginning of Period (in dollars per share) $ 42.57  
Warrants, Granted (in dollars per share) 0  
Warrants, Exercised (in dollars per share) 0  
Warrants, Forfeited (in dollars per share) 0  
Warrants, Expired (in dollars per share) 0  
Warrants Outstanding, End of Period (in dollars per share) 42.57 $ 42.57
Weighted Average Exercise Price, Warrants Vested And Expected To Vest 42.57  
Warrants, Vested, Weighted Average Exercise Price (in dollars per share) $ 42.57  
Warrants, Weighted Average Contractual Term and Intrinsic Value    
Warrants, Outstanding, Weighted Average Remaining Contractual Term 3 years 1 month 17 days 3 years 4 months 13 days
Warrants, Vested and expected to vest, Weighted Average Remaining Contractual Term 3 years 1 month 17 days  
Warrants, Vested, Weighted Average Remaining Contractual Term 3 years 1 month 17 days  
Warrants Outstanding, Aggregate Intrinsic Value $ 0 $ 0
Warrants, Vested and expected to vest, Aggregate Intrinsic Value 0  
Warrants, Vested, Aggregate Intrinsic Value $ 0