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License Agreements (Details) - USD ($) $ in Thousands | Sep. 30, 2023 | Jul. 31, 2023 | Mar. 31, 2022 | Oct. 31, 2021 | Dec. 31, 2016
--- | --- | --- | --- | --- | ---
Impilo |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Investment owned (in shares) |  | 766,000 |  |  |
Sanford Burnham Prebys | Impilo |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Investment owned (in shares) |  | 191,500 |  |  |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Shares issued under license agreement (in shares) |  |  |  |  | 382,030
Annual license maintenance fee |  |  |  | $ 20,000 | $ 10,000
Annual license maintenance fee, year seven |  |  |  |  | 20,000
Potential milestone payments |  |  |  | $ 23,200 | $ 10,600
Royalties, net of sales |  |  |  | 4.00% | 4.00%
Sublicensing fee |  |  |  |  | 25.00%
Annual license maintenance fee, year four |  |  |  | $ 30,000 |
Shares held by third party (in shares) | 382,030 |  |  |  |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  |  | 10.00% |
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  |  | 25.00% |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Potential milestone payments |  |  | $ 1,200 |  |
Royalties, net of sales |  |  | 1.50% |  |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  | 10.00% |  |
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  | 20.00% |  |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Annual license maintenance fee |  |  |  | $ 20,000 |
Potential milestone payments |  |  |  | $ 5,000 |
Royalties, net of sales |  |  |  | 2.00% |
Annual license maintenance fee, year four |  |  |  | $ 50,000 |
Shares held by third party (in shares) | 43,236 |  |  |  |
Annual license maintenance fee, years two and three |  |  |  | 25,000 |
Annual license maintenance fee, after first sale |  |  |  | 150,000 |
Change of control fee |  |  |  | $ 300 |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | CEND |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Shares issued (in shares) | 43,236 |  |  |  |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  |  | 3.00% |
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |
Sublicensing fee |  |  |  | 20.00% |

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