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License Agreements (Details) - USD ($)
$ in Thousands
Sep. 30, 2023
Jul. 31, 2023
Mar. 31, 2022
Oct. 31, 2021
Dec. 31, 2016
Impilo          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Investment owned (in shares)   766,000      
Sanford Burnham Prebys | Impilo          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Investment owned (in shares)   191,500      
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Shares issued under license agreement (in shares)         382,030
Annual license maintenance fee       $ 20,000 $ 10,000
Annual license maintenance fee, year seven         20,000
Potential milestone payments       $ 23,200 $ 10,600
Royalties, net of sales       4.00% 4.00%
Sublicensing fee         25.00%
Annual license maintenance fee, year four       $ 30,000  
Shares held by third party (in shares) 382,030        
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee       10.00%  
Sanford Burnham Prebys | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee       25.00%  
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Potential milestone payments     $ 1,200    
Royalties, net of sales     1.50%    
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee     10.00%    
University of California at San Diego | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee     20.00%    
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Annual license maintenance fee       $ 20,000  
Potential milestone payments       $ 5,000  
Royalties, net of sales       2.00%  
Annual license maintenance fee, year four       $ 50,000  
Shares held by third party (in shares) 43,236        
Annual license maintenance fee, years two and three       25,000  
Annual license maintenance fee, after first sale       150,000  
Change of control fee       $ 300  
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | CEND          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Shares issued (in shares) 43,236        
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Minimum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee       3.00%  
Massachusetts Institute of Technology | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Maximum          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Sublicensing fee       20.00%