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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Cash flows from operating activities:    
Net loss $ (5,401) $ (6,187)
Adjustments to reconcile net loss to net cash used in operating activities:    
Share-based compensation 454 675
Depreciation and amortization 46 48
Loss on disposal of fixed assets 0 3
Loss from equity method investment 100 0
Amortization/accretion on marketable securities (152) (167)
Changes in operating assets and liabilities:    
Prepaid and other current assets (872) (1,652)
Other assets 41 167
Accounts payable, accrued liabilities and other liabilities (1,243) (1,083)
Net cash used in operating activities (7,027) (8,196)
Cash flows from investing activities:    
Purchase of marketable securities (18,824) (30,121)
Sale of marketable securities 25,360 34,410
Investment in Impilo Therapeutics (100) 0
Net cash provided by investing activities 6,436 4,289
Cash flows from financing activities:    
Tax withholding payments on net share settlement equity awards (142) (85)
Net cash used in financing activities (142) (85)
Effect of exchange rate changes on cash (55) (7)
Net decrease in cash and cash equivalents (788) (3,999)
Cash and cash equivalents at beginning of period 22,593 32,154
Cash and cash equivalents at end of period $ 21,805 $ 28,155