<SEC-DOCUMENT>0001209191-16-124799.txt : 20160601
<SEC-HEADER>0001209191-16-124799.hdr.sgml : 20160601
<ACCEPTANCE-DATETIME>20160601185019
ACCESSION NUMBER:		0001209191-16-124799
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160601
FILED AS OF DATE:		20160601
DATE AS OF CHANGE:		20160601

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Clearside Biomedical, Inc.
		CENTRAL INDEX KEY:			0001539029
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				452437375
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1220 OLD ALPHARETTA RD
		STREET 2:		SUITE 300
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30005
		BUSINESS PHONE:		678-270-4005

	MAIL ADDRESS:	
		STREET 1:		1220 OLD ALPHARETTA RD
		STREET 2:		SUITE 300
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30005

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RusnanoMedInvest LLC
		CENTRAL INDEX KEY:			0001579466
		STATE OF INCORPORATION:			1Z
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161690543

	BUSINESS ADDRESS:	
		STREET 1:		SOKOLNICHESKYI VAL STR. OFFICE VII
		CITY:			MOSCOW
		STATE:			1Z
		ZIP:			107113 38
		BUSINESS PHONE:		074955453912

	MAIL ADDRESS:	
		STREET 1:		SOKOLNICHESKYI VAL STR. OFFICE VII
		CITY:			MOSCOW
		STATE:			1Z
		ZIP:			107113 38

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RMI Investments S.a.r.l.
		CENTRAL INDEX KEY:			0001579787
		STATE OF INCORPORATION:			1Z
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161690544

	BUSINESS ADDRESS:	
		STREET 1:		17, RUE DES JARDINIERS
		CITY:			LUXEMBOURG
		STATE:			N4
		ZIP:			L-1835
		BUSINESS PHONE:		79851530799

	MAIL ADDRESS:	
		STREET 1:		7, ROBERT STUMPER
		CITY:			GRAND DUCHY
		STATE:			N4
		ZIP:			L-2557
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2016-06-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001539029</issuerCik>
        <issuerName>Clearside Biomedical, Inc.</issuerName>
        <issuerTradingSymbol>CLSD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001579787</rptOwnerCik>
            <rptOwnerName>RMI Investments S.a.r.l.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>7, ROBERT STUMPER</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GRAND DUCHY</rptOwnerCity>
            <rptOwnerState>N4</rptOwnerState>
            <rptOwnerZipCode>L-2557</rptOwnerZipCode>
            <rptOwnerStateDescription>LUXEMBOURG</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001579466</rptOwnerCik>
            <rptOwnerName>RusnanoMedInvest LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>44, BLDG. 1, KRASNOBOGATYRSKAYA STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MOSCOW</rptOwnerCity>
            <rptOwnerState>1Z</rptOwnerState>
            <rptOwnerZipCode>107076</rptOwnerZipCode>
            <rptOwnerStateDescription>RUSSIAN FEDERATION</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>335769</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series B Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F3"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F3"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1179398</value>
                    <footnoteId id="F4"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The number of shares of common stock reflects a 1-for-2.2 reverse stock split of the Issuer's common stock effected on May 11, 2016.</footnote>
        <footnote id="F2">The Reporting Person is a wholly-owned subsidiary of Rusnano MedInvest LLC (&quot;RMI LLC&quot;). RMI LLC is the beneficiary of the Reporting Person.</footnote>
        <footnote id="F3">Each share of the Series B Preferred Stock is convertible, at any time, at the holder's election, into 0.454545 shares of the Issuer's common stock. In addition, effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of Series B Preferred Stock will automatically convert into 0.454545 shares of the Issuer's common stock. The Series B Preferred Stock has no expiration date.</footnote>
        <footnote id="F4">The number of underlying shares of common stock reflects a 1-for-2.2 reverse stock split of the Issuer's common stock effected on May 11, 2016.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Vladimir Gurdus, CEO of RMI Partners, LLC, Managing Company for Rusnano MedInvest, LLC, its Category A Manager</signatureName>
        <signatureDate>2016-06-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Vladimir Gurdus, CEO of RMI Partners, LLC its Managing Company</signatureName>
        <signatureDate>2016-06-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
