<SEC-DOCUMENT>0001209191-16-126263.txt : 20160607
<SEC-HEADER>0001209191-16-126263.hdr.sgml : 20160607
<ACCEPTANCE-DATETIME>20160607163800
ACCESSION NUMBER:		0001209191-16-126263
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20160607
FILED AS OF DATE:		20160607
DATE AS OF CHANGE:		20160607

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Clearside Biomedical, Inc.
		CENTRAL INDEX KEY:			0001539029
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				452437375
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1220 OLD ALPHARETTA RD
		STREET 2:		SUITE 300
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30005
		BUSINESS PHONE:		678-270-4005

	MAIL ADDRESS:	
		STREET 1:		1220 OLD ALPHARETTA RD
		STREET 2:		SUITE 300
		CITY:			ALPHARETTA
		STATE:			GA
		ZIP:			30005

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Thorp Clay
		CENTRAL INDEX KEY:			0001592380

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701697

	MAIL ADDRESS:	
		STREET 1:		C/O HATTERAS VENTURE PARTNERS III, LP
		STREET 2:		280 S. MANGUM ST., SUITE 350
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27701

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INGRAM ROBERT ALEXANDER
		CENTRAL INDEX KEY:			0001219890

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701698

	MAIL ADDRESS:	
		STREET 1:		280 S. MANGUM STREET
		STREET 2:		SUITE 350
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27701

	FORMER NAME:	
		FORMER CONFORMED NAME:	INGRAM ROBERT A
		DATE OF NAME CHANGE:	20030222

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Crumpler John
		CENTRAL INDEX KEY:			0001674107

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701701

	MAIL ADDRESS:	
		STREET 1:		280 S. MANGUM STREET
		STREET 2:		SUITE 350
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27701

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hatteras Venture Affiliates III Lp
		CENTRAL INDEX KEY:			0001390738

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701702

	BUSINESS ADDRESS:	
		STREET 1:		1822 E NC 54
		STREET 2:		Ste 250
		CITY:			Durham
		STATE:			NC
		ZIP:			27713
		BUSINESS PHONE:		9194840730

	MAIL ADDRESS:	
		STREET 1:		1822 E NC 54
		STREET 2:		Ste 250
		CITY:			Durham
		STATE:			NC
		ZIP:			27713

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hatteras Ventures Partners III LP
		CENTRAL INDEX KEY:			0001390733

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701703

	BUSINESS ADDRESS:	
		STREET 1:		1822 E NC 54 Ste 250
		CITY:			Durham
		STATE:			NC
		ZIP:			27713
		BUSINESS PHONE:		9194840730

	MAIL ADDRESS:	
		STREET 1:		1822 E NC 54 Ste 250
		CITY:			Durham
		STATE:			NC
		ZIP:			27713

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Hatteras Venture Advisors III, LLC
		CENTRAL INDEX KEY:			0001674177
		STATE OF INCORPORATION:			NC
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701704

	BUSINESS ADDRESS:	
		STREET 1:		280 S. MANGUM STREET, SUITE 350
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27701
		BUSINESS PHONE:		919-484-0730

	MAIL ADDRESS:	
		STREET 1:		280 S. MANGUM STREET, SUITE 350
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27701

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Reed Douglas MD
		CENTRAL INDEX KEY:			0001291262

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701700

	MAIL ADDRESS:	
		STREET 1:		C/O VECTOR FUND MANAGEMENT
		STREET 2:		1751 LAKE COOK ROAD, SUITE 350
		CITY:			DEERFIELD
		STATE:			IL
		ZIP:			60015

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LEE KENNETH B JR
		CENTRAL INDEX KEY:			0001208570

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37783
		FILM NUMBER:		161701699
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                    <value>See Footnotes</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F8"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Series C Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-06-07</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>337898</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>162661</value>
                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F9"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant to Purchase Common Stock (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.022</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-06-07</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>X</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>19900</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2014-04-28</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F10"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>19900</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Hatteras Venture Partners III, LP</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F11"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant to Purchase Common Stock (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.022</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2016-06-07</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>X</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>1805</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2014-04-28</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F10"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1805</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Hatteras Venture Affiliates III, LP</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F12"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The total represents shares received upon conversion of shares of Series A Preferred Stock, Series A-1 Preferred Stock, Series B Preferred Stock and Series C Preferred Stock.</footnote>
        <footnote id="F2">Effective immediately prior to the closing of the Issuer's initial public offering of its common stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock and Series B Preferred Stock automatically converted into 0.454545 shares of the Issuer's common stock, and each share of Series C Preferred Stock automatically converted into 0.4814 shares of the Issuer's common stock. The Preferred Stock had no expiration date.</footnote>
        <footnote id="F3">The reportable securities are owned directly by Hatteras Venture Partners III, LP (&quot;HVP&quot;) and Hatteras Venture Affiliates III, LP (&quot;HVA&quot;). Hatteras Venture Advisors III, LLC is the general partner of HVP and HVA (the &quot;GP&quot;). The shares directly held by HVP and HVA are indirectly held by the individual managing members of GP (each, a &quot;GP Managing Member&quot; and collectively, the &quot;GP Managing Members&quot;). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP and HVA. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein.</footnote>
        <footnote id="F4">On June 7, 2016, HVP and HVA exercised warrants to purchase an aggregate of 21,705 shares of Issuer's common stock for $0.022 per share. HVP and HVA paid the exercise price on a cashless basis, resulting in the Issuer's withholding of an aggregate of 69 of the warrant shares to pay the exercise price and
issuing to the reporting person the remaining 21,636 shares.</footnote>
        <footnote id="F5">HVP holds 1,634,603 shares and HVA holds 148,417 shares of the Issuer's Common Stock directly.</footnote>
        <footnote id="F6">HVP held 1,866,418 shares and HVA held 169,489 shares of the Issuer's Series A Preferred Stock directly</footnote>
        <footnote id="F7">HVP held 631,997 shares and HVA held 57,391 shares of the Issuer's Series A-1 Preferred Stock directly.</footnote>
        <footnote id="F8">HVP held 396,920 shares and HVA held 36,020 shares of the Issuer's Series B Preferred Stock directly.</footnote>
        <footnote id="F9">HVP held 309,768 shares and HVA held 28,130 shares of the Issuer's Series C Preferred Stock directly.</footnote>
        <footnote id="F10">This warrant would have expired upon the closing of the Issuer's initial public offering.</footnote>
        <footnote id="F11">The reportable securities were owned directly by HVP.</footnote>
        <footnote id="F12">The reportable securities are owned directly by HVA.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Hatteras Venture Advisors III, LLC</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Hatteras Venture Advisors III, LLC, the general partner of Hatteras Venture Partners III, LP</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Hatteras Venture Advisors III, LLC, the general partner of Hatteras Venture Affiliates III, LP</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for John Crumpler</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Douglas Reed</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Kenneth Lee</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Robert Ingram</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brian F. Leaf, Attorney-in-Fact for Clay Thorp</signatureName>
        <signatureDate>2016-06-07</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
