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Schedule of Effective Income Tax Rate Reconciliation (Details) - USD ($) | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Income Tax Disclosure [Abstract] |  |  |  |
Federal income tax benefit at statutory rate | $ (845,722) |  | $ (2,733,779) |
State income tax benefit | (222,707) |  | (719,896) |
Permanent differences | 3,157 |  | 11,920 |
Change in valuation allowance | 1,246,403 |  | 3,685,697 |
Research and development tax credit adjustment | (131,681) |  | (131,681) |
Other | (49,450) |  | (112,261) |
Total income tax expense |  |  |  |

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