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Research and Development Collaborations (Details)	1 Months Ended		12 Months Ended
	Sep. 30, 2016 USD ($) program	Jun. 30, 2003 USD ($)	Dec. 31, 2024 USD ($) product	Dec. 31, 2023 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues			$ 10,908,000	$ 10,023,000
Accounts receivable			$ 3,349,000	2,794,000
Number of programs licensed | program	4
Royalty fees receivable (as a percent)			10.00%
Genentech, Inc.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Amount received for specified clinical development and regulatory objectives			$ 59,000,000.0
Percentage of royalty rate decrease		2.00%
Accounts receivable			3,300,000	2,700,000
Genentech, Inc. | Royalties
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenues			$ 10,900,000	$ 9,900,000
Genentech, Inc. | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Eligible to receive contingent cash milestone payments (up to)		$ 115,000,000.0
Percentage of royalty on net sales		7.50%
Genentech, Inc. | Minimum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of royalty on net sales		5.00%
Aurigene Discovery Technologies Limited
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Waived payment of milestone and other payments (up to)	$ 24,500,000
Number of products required to commercialize | product			1
Aurigene Discovery Technologies Limited | Third and Fourth Programs
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Additional funding	$ 2,000,000.0
Aurigene Discovery Technologies Limited | IRAK4, PD1/VISTA,PD1/TIM3 Program
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Waived payment of milestone and other payments (up to)			$ 42,500,000

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