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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Cash flows from operating activities:    
Net loss $ (43,389) $ (47,413)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 203 255
Non-cash lease expense 1,274 1,344
Stock-based compensation expense 5,927 6,000
Non-cash activity related to the sale of future royalties 154 (340)
Amortization of premiums and discounts on investments (16) (1,059)
Changes in operating assets and liabilities:    
Accounts receivable (555) 181
Prepaid expenses and other assets 139 405
Accounts payable and accrued and other liabilities (2,077) 3,340
Operating lease liability (1,223) (1,147)
Total adjustments 3,826 8,979
Net cash used in operating activities (39,563) (38,434)
Cash flows from investing activities:    
Purchases of investments (18,098) (70,340)
Sales and maturities of investments 47,540 108,126
Net cash provided by investing activities 29,442 37,786
Cash flows from financing activities:    
Proceeds from issuance of common stock and Warrants, net of issuance costs 12,023 14,117
Payment of liability of future royalties, net of imputed interest (8,586) (6,537)
Net cash provided by financing activities 3,437 7,580
Net increase (decrease) in cash and cash equivalents and restricted cash (6,684) 6,932
Cash and cash equivalents and restricted cash, beginning of period 27,225 20,293
Cash and cash equivalents and restricted cash, end of period 20,541 27,225
Supplemental cash flow data:    
Issuance costs in accounts payable 50 0
Cash paid for interest 461 2,359
Increase in right-of-use assets and operating lease liabilities resulting from lease modification (1,383) 0
Reconciliation of cash, cash equivalents and restricted cash:    
Cash and cash equivalents 19,997 26,681
Restricted cash, long-term $ 544 $ 544