XML 41 R30.htm IDEA: XBRL DOCUMENT
v3.26.1

Stockholders' Equity - Narrative (Details) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 3 Months Ended |  |
--- | --- | --- | --- | --- | ---
Mar. 17, 2026 USD ($) shares | Apr. 30, 2026 $ / shares shares | Jan. 31, 2026 USD ($) $ / shares shares | Jul. 31, 2025 USD ($) $ / shares shares | Mar. 31, 2025 USD ($) $ / shares shares | Oct. 31, 2024 USD ($) $ / shares shares | Feb. 29, 2024 USD ($) | Mar. 31, 2026 USD ($) $ / shares shares | Mar. 31, 2025 USD ($) $ / shares shares | Feb. 28, 2026 shares | Dec. 31, 2025 $ / shares shares
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized (in shares) | shares |  |  |  |  |  |  |  | 283,757,150 |  | 68,343,750 | 68,343,750
Common stock, fair value |  |  |  |  |  |  |  | $ 2,400 |  |  |
Preferred stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 0.01 |  |  | $ 0.01
Convertible preferred stock, maximum beneficial ownership upon conversion, option one (as a percent) | 4.99% |  |  |  |  |  |  |  |  |  |
Convertible preferred stock, maximum beneficial ownership upon conversion, option two (as a percent) | 9.99% |  |  |  |  |  |  |  |  |  |
Convertible preferred stock, maximum beneficial ownership upon conversion, option three (as a percent) | 19.99% |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of preferred stock |  |  | $ 2,500 |  |  |  |  |  |  |  |
Issuance costs associated with warrant liabilities |  |  |  |  |  |  |  | $ 1,406 | $ 0 |  |
Warrant liability |  |  |  |  |  |  |  | 1,897 |  |  |
Loss (gain) on fair value adjustment of warrants |  |  |  |  |  |  |  | $ (12,757) | $ 0 |  |
Common stock, par value (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 0.01 |  |  | $ 0.01
Common Stock |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Convertible preferred stock, shares issued upon conversion (in shares) | shares | 1,333.33 |  |  |  |  |  |  |  |  |  |
Stock issued during period value new issues (in shares) | shares | 26,243,754 |  |  |  |  |  |  |  |  |  |
Series B Preferred Stock |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Payment of issuance costs on direct placement |  |  |  |  |  |  |  | $ 200 |  |  |
Stock Issued During Period, Preferred Stock, Fair Value |  |  |  |  |  |  |  | 2,500 |  |  |
Pre Funded Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrants issued (in shares) | shares | 682,921 |  |  |  |  |  |  |  |  |  |
Series A Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of warrants |  |  | 8,200 |  |  |  |  |  |  |  |
Warrant liability | $ 16,700 |  |  |  |  |  |  |  |  |  |
Loss (gain) on fair value adjustment of warrants |  |  |  |  |  |  |  | (14,500) |  |  |
Series B Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of warrants |  |  | $ 3,700 |  |  |  |  |  |  |  |
Loss (gain) on fair value adjustment of warrants |  |  |  |  |  |  |  | 1,800 |  |  |
Warrant term following announcement |  |  | 30 days |  |  |  |  |  |  |  |
Class of warrant or right, percentage of exercise price of warrants or rights reducible, minimum |  |  | 0.50 |  |  |  |  |  |  |  |
Warrants and rights additional extension outstanding, term |  |  | 30 days |  |  |  |  |  |  |  |
Series C Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Proceeds from issuance of warrants |  |  | $ 5,900 |  |  |  |  |  |  |  |
Warrant liability | $ 11,900 |  |  |  |  |  |  |  |  |  |
Loss (gain) on fair value adjustment of warrants |  |  |  |  |  |  |  | (14,500) |  |  |
January 2026 Common Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Issuance costs associated with warrant liabilities |  |  |  |  |  |  |  | 1,400 |  |  |
January 2026 Pre-Funded Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Warrant liability |  |  |  |  |  |  |  | $ 100 |  |  |
Common Stock |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Stock issued during period value new issues (in shares) | shares |  |  |  |  |  |  |  |  | 1,974,432 |  |
Common Stock | Subsequent Event |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock exchange offer (in shares) | shares |  | 1,000,000 |  |  |  |  |  |  |  |  |
Common stock, par value (in dollars per share) | $ / shares |  | $ 0.01 |  |  |  |  |  |  |  |  |
Common Stock | Pre Funded Warrants | Subsequent Event |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  | 1,000,000 |  |  |  |  |  |  |  |  |
Private Placement |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of shares sold (in shares) | shares |  |  | 20,195 |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  |  | 3,076,921 | 8,316,882 |  |  |  | 8,316,882 |  |
Exercise price of warrants (in dollars per share) | $ / shares |  |  |  | $ 2.15 | $ 2.41 |  |  |  | $ 2.41 |  |
Class of warrant or right, expiration period |  |  |  | 5 years | 5 years |  |  |  |  |  |
Sale of equity, price per share (in dollars per share) | $ / shares |  |  |  | $ 2.275 | $ 2.41 | $ 5.045 |  |  | $ 2.41 |  |
Aggregate net proceeds from equity offering |  |  |  | $ 6,100 | $ 8,800 | $ 10,800 |  |  |  |  |
Preferred stock, par value (in dollars per share) | $ / shares |  |  | $ 0.01 |  |  |  |  |  |  |  |
Private Placement | Unregistered Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  |  |  |  | 2,398,414 |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ / shares |  |  |  |  |  | $ 4.92 |  |  |  |  |
Class of warrant or right, expiration period |  |  |  |  |  | 5 years |  |  |  |  |
Private Placement | Pre-Funded Unregistered Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  |  | 1,538,461 | 2,184,009 |  |  |  | 2,184,009 |  |
Private Placement | Pre Funded Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ / shares |  |  |  | $ 0.01 | $ 0.01 |  |  |  | $ 0.01 |  |
Warrants, fair value |  |  |  | $ 1,800 | $ 2,400 |  |  |  | $ 2,400 |  |
Exercise of warrants, number of shares issued (in shares) | shares |  |  |  |  |  |  |  | 764,000 |  |  |
Private Placement | Series A Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 26,926,675 |  |  |  |  |  |  |  |
Private Placement | Series B Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 26,926,675 |  |  |  |  |  |  |  |
Private Placement | Series C Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 26,926,675 |  |  |  |  |  |  |  |
Private Placement | Common Stock |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Number of shares sold (in shares) | shares |  |  |  | 1,538,460 | 1,974,432 | 2,398,414 |  |  |  |  |
Purchase price share (in shares) | shares |  |  |  | 1 | 1 | 1 |  |  | 1 |  |
October 2024 Offerings |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, fair value |  |  |  |  |  | $ 6,000 |  |  |  |  |
Warrants, fair value |  |  |  |  |  | $ 4,800 |  |  |  |  |
March 2025 Offerings |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Purchase price share (in shares) | shares |  |  |  |  | 1 |  |  |  | 1 |  |
Common stock, fair value |  |  |  | $ 1,800 | $ 2,200 |  |  |  | $ 2,200 |  |
Warrants, fair value |  |  |  | $ 2,500 | $ 4,200 |  |  |  | $ 4,200 |  |
Registered Direct Offering |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Class of warrant or right, purchase price (in dollars per share) | $ / shares |  |  |  | $ 2.265 | $ 2.40 |  |  |  | $ 2.40 |  |
July 2025 Offerings |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Purchase price share (in shares) | shares |  |  |  | 1 |  |  |  |  |  |  |
January 2026 PIPE Financing |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants (in dollars per share) | $ / shares |  |  | $ 0.75 |  |  |  |  |  |  |  |
Class of warrant or right, purchase price (in dollars per share) | $ / shares |  |  | $ 1,000 |  |  |  |  |  |  |  |
Proceeds from issuance of equity |  |  |  |  |  |  |  | $ 20,200 |  |  |
Payment of issuance costs on direct placement |  |  |  |  |  |  |  | $ 1,600 |  |  |
Consideration received on transaction |  |  | $ 18,600 |  |  |  |  |  |  |  |
January 2026 PIPE Financing | Series A Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 1,333.33 |  |  |  |  |  |  |  |
January 2026 PIPE Financing | Series B Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 1,333.33 |  |  |  |  |  |  |  |
January 2026 PIPE Financing | Series C Warrants |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Unregistered warrants issued (in shares) | shares |  |  | 1,333.33 |  |  |  |  |  |  |  |
Cantor Fitzgerald & Co | Common Stock |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Sale of stock, maximum authorized amount |  |  |  |  |  |  | $ 100,000 |  |  |  |
Cantor Fitzgerald & Co | Common Stock | Private Placement |  |  |  |  |  |  |  |  |  |  |
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Compensation fee |  |  |  |  |  |  | 3.00% |  |  |  |
Number of shares sold (in shares) | shares |  |  |  |  |  |  |  | 0 | 0 |  |
Sale of stock remaining authorized amount |  |  |  |  |  |  |  | $ 98,800 |  |  |
Sale of stock, maximum public float |  |  |  |  |  |  |  | $ 75,000 |  |  |
Sale of stock, sale restriction period |  |  |  |  |  |  |  | 12 months |  |  |
Stock sale agreement, maximum percentage of public float |  |  |  |  |  |  |  | 33.00% |  |  |

X
- Definition Class of Warrant or Right, Exercise of Warrant, Number of Shares Issued + References No definition available. + Details
Name: | cris_ClassOfWarrantOrRightExerciseOfWarrantNumberOfSharesIssued
Namespace Prefix: | cris_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

X
- Definition Class Of Warrant Or Right, Expiration Period + References No definition available. + Details
Name: | cris_ClassOfWarrantOrRightExpirationPeriod
Namespace Prefix: | cris_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition Class Of Warrant Or Right, Number Of Warrants Issued + References No definition available. + Details
Name: | cris_ClassOfWarrantOrRightNumberOfWarrantsIssued
Namespace Prefix: | cris_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- Definition Class of Warrant or Right, Percentage of Exercise Price of Warrants or Rights Reduced, Minimum + References No definition available. + Details
Name: | cris_ClassOfWarrantOrRightPercentageOfExercisePriceOfWarrantsOrRightsReducedMinimum
Namespace Prefix: | cris_
Data Type: | xbrli:pureItemType
Balance Type: | na
Period Type: | instant

X
- Definition Class of Warrant or Right, Purchase Price + References No definition available. + Details
Name: | cris_ClassOfWarrantOrRightPurchasePrice
Namespace Prefix: | cris_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition Convertible Preferred Stock, Maximum Beneficial Ownership, Option One + References No definition available. + Details
Name: | cris_ConvertiblePreferredStockMaximumBeneficialOwnershipOptionOne
Namespace Prefix: | cris_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Convertible Preferred Stock, Maximum Beneficial Ownership, Option Three + References No definition available. + Details
Name: | cris_ConvertiblePreferredStockMaximumBeneficialOwnershipOptionThree
Namespace Prefix: | cris_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Convertible Preferred Stock, Maximum Beneficial Ownership, Option Two + References No definition available. + Details
Name: | cris_ConvertiblePreferredStockMaximumBeneficialOwnershipOptionTwo
Namespace Prefix: | cris_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Issuance Costs Associated With Warrant Liabilities + References No definition available. + Details
Name: | cris_IssuanceCostsAssociatedWithWarrantLiabilities
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Purchase Price Share + References No definition available. + Details
Name: | cris_PurchasePriceShare
Namespace Prefix: | cris_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- Definition Sale of Equity, Consideration Received on Transaction + References No definition available. + Details
Name: | cris_SaleOfEquityConsiderationReceivedOnTransaction
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Sale of Equity, Price Per Share + References No definition available. + Details
Name: | cris_SaleOfEquityPricePerShare
Namespace Prefix: | cris_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition Sale of Stock Agreement, Maximum Percentage of Public Float + References No definition available. + Details
Name: | cris_SaleOfStockAgreementMaximumPercentageOfPublicFloat
Namespace Prefix: | cris_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Sale of Stock, Authorized Maximum Amount + References No definition available. + Details
Name: | cris_SaleOfStockAuthorizedMaximumAmount
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Stock Issued During Period, Common Stock, Fair Value + References No definition available. + Details
Name: | cris_StockIssuedDuringPeriodCommonStockFairValue
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Stock Issued During Period, Preferred Stock, Fair Value + References No definition available. + Details
Name: | cris_StockIssuedDuringPeriodPreferredStockFairValue
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Stock Issued During Period, Shares, Stock Exchange Offer + References No definition available. + Details
Name: | cris_StockIssuedDuringPeriodSharesStockExchangeOffer
Namespace Prefix: | cris_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

X
- Definition Stock Sale Agreement, Compensation Fee, Percentage Of Gross Proceeds + References No definition available. + Details
Name: | cris_StockSaleAgreementCompensationFeePercentageOfGrossProceeds
Namespace Prefix: | cris_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

X
- Definition Stock Sale Agreement, Remaining Authorized Amount + References No definition available. + Details
Name: | cris_StockSaleAgreementRemainingAuthorizedAmount
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Stock Sale Agreement, Sale Restriction, Maximum Public Float + References No definition available. + Details
Name: | cris_StockSaleAgreementSaleRestrictionMaximumPublicFloat
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Stock Sale Agreement, Sale Restriction, Period + References No definition available. + Details
Name: | cris_StockSaleAgreementSaleRestrictionPeriod
Namespace Prefix: | cris_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | duration

X
- Definition Warrant And Rights Outstanding, Term Following Announcement + References No definition available. + Details
Name: | cris_WarrantAndRightsOutstandingTermFollowingAnnouncement
Namespace Prefix: | cris_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | instant

X
- Definition Warrant Liability, Fair Value Disclosure + References No definition available. + Details
Name: | cris_WarrantLiabilityFairValueDisclosure
Namespace Prefix: | cris_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Warrants and Rights Outstanding, Additional Extension Term + References No definition available. + Details
Name: | cris_WarrantsAndRightsOutstandingAdditionalExtensionTerm
Namespace Prefix: | cris_
Data Type: | xbrli:durationItemType
Balance Type: | na
Period Type: | instant

X
- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 815 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 8A -Publisher FASB -URI https://asc.fasb.org/1943274/2147480434/815-10-50-8A Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-2 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 235 -SubTopic 10 -Name Accounting Standards Codification -Section S50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480738/235-10-S50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 480 -SubTopic 10 -Name Accounting Standards Codification -Section S50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479857/480-10-S50-1 Reference 5: http://www.xbrl.org/2003/role/exampleRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (d) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 Reference 6: http://www.xbrl.org/2003/role/recommendedDisclosureRef -Topic 272 -SubTopic 10 -Name Accounting Standards Codification -Section 45 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org/1943274/2147483014/272-10-45-3 Reference 7: http://www.xbrl.org/2003/role/disclosureRef -Topic 272 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482987/272-10-50-1 Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 235 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08(d)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480678/235-10-S99-1 Reference 9: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 Reference 10: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 Reference 11: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (e) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 Reference 12: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (h) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 Reference 13: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 14 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-14 Reference 14: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 18 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-18 Reference 15: http://www.xbrl.org/2003/role/disclosureRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(27)(b)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 16: http://www.xbrl.org/2003/role/disclosureRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 17: http://www.xbrl.org/2003/role/disclosureRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 18: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(2)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 Reference 19: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(1)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 Reference 20: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(2)(i)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 Reference 21: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(2)(ii)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 + Details
Name: | us-gaap_ClassOfStockLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Exercise price per share or per unit of warrants or rights outstanding. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 235 -SubTopic 10 -Name Accounting Standards Codification -Section S50 -Paragraph 1 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480738/235-10-S50-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 235 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08(h)(4)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480678/235-10-S99-1 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-3 + Details
Name: | us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition Number of securities into which the class of warrant or right may be converted. For example, but not limited to, 500,000 warrants may be converted into 1,000,000 shares. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-3 + Details
Name: | us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- Definition Face amount or stated value per share of common stock. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 + Details
Name: | us-gaap_CommonStockParOrStatedValuePerShare
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition The maximum number of common shares permitted to be issued by an entity's charter and bylaws. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 210 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.6-04(16)(a)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479170/946-210-S99-1 + Details
Name: | us-gaap_CommonStockSharesAuthorized
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- Definition Number of shares issued for each share of convertible preferred stock that is converted. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(27)) -SubTopic 10 -Topic 210 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-3 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 6 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-6 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 16 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-16 + Details
Name: | us-gaap_ConvertiblePreferredStockSharesIssuedUponConversion
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- Definition Amount of expense (income) related to adjustment to fair value of warrant liability. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (b) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 + Details
Name: | us-gaap_FairValueAdjustmentOfWarrants
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The cash outflow for cost incurred directly with the issuance of an equity security. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-15 + Details
Name: | us-gaap_PaymentsOfStockIssuanceCosts
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Face amount or stated value per share of preferred stock nonredeemable or redeemable solely at the option of the issuer. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 13 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-13 + Details
Name: | us-gaap_PreferredStockParOrStatedValuePerShare
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:perShareItemType
Balance Type: | na
Period Type: | instant

X
- Definition Proceeds from issuance of capital stock which provides for a specific dividend that is paid to the shareholders before any dividends to common stockholders and which takes precedence over common stockholders in the event of liquidation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 14 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-14 + Details
Name: | us-gaap_ProceedsFromIssuanceOfPreferredStockAndPreferenceStock
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The cash inflow from issuance of rights to purchase common shares at predetermined price (usually issued together with corporate debt). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 14 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-14 + Details
Name: | us-gaap_ProceedsFromIssuanceOfWarrants
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 14 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-14 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(1)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 + Details
Name: | us-gaap_ProceedsFromIssuanceOrSaleOfEquity
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Cash received on stock transaction after deduction of issuance costs. + References No definition available. + Details
Name: | us-gaap_SaleOfStockConsiderationReceivedOnTransaction
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition The number of shares issued or sold by the subsidiary or equity method investee per stock transaction. + References No definition available. + Details
Name: | us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

X
- Definition Number of new stock issued during the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -SubTopic 10 -Topic 505 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481112/505-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(28)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 505 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478448/946-505-50-2 Reference 5: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 220 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-09(4)(b)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479134/946-220-S99-3 Reference 6: http://www.xbrl.org/2003/role/disclosureRef -Topic 946 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 3 -Subparagraph (SX 210.6-03(i)(1)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479886/946-10-S99-3 Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480008/505-10-S99-1 + Details
Name: | us-gaap_StockIssuedDuringPeriodSharesNewIssues
Namespace Prefix: | us-gaap_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

X
- Definition Fair value portion of warrants not settleable in cash classified as equity. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2E -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2E + Details
Name: | us-gaap_WarrantsNotSettleableInCashFairValueDisclosure
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Details
Name: | us-gaap_StatementClassOfStockAxis=us-gaap_CommonStockMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_StatementClassOfStockAxis=us-gaap_SeriesBPreferredStockMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_PreFundedWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_SeriesAWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_SeriesBWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_SeriesCWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_January2026CommonWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_January2026PreFundedWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_StatementEquityComponentsAxis=us-gaap_CommonStockMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=us-gaap_PrivatePlacementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_UnregisteredWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ClassOfWarrantOrRightAxis=cris_PreFundedUnregisteredWarrantsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=cris_October2024OfferingsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=cris_March2025OfferingsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=cris_RegisteredDirectOfferingMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=cris_July2025OfferingsMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_SubsidiarySaleOfStockAxis=cris_January2026PIPEFinancingMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | srt_CounterpartyNameAxis=cris_CantorFitzgeraldAndCoMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_AwardTypeAxis=us-gaap_CommonStockMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |