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Stock Plans and Stock-Based Compensation (Tables) | 3 Months Ended
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Mar. 31, 2026
Share-Based Payment Arrangement [Abstract] |
Schedule of Stock Option | A summary of stock option activity under the 2026 Plan, 2010 Plan, and Inducement Awards are summarized as follows:
| Number of Shares |  | Weighted Average Exercise Price per Share |  | Weighted Average Remaining Contractual Life |  | Aggregate Intrinsic Value
Outstanding, December 31, 2025 | 2,429,064 |  |  | $ | 16.59 |  |  | 7.80 |  | $ | — |
Granted | — |  |  | — |  |  |  |  |
Exercised | — |  |  | — |  |  |  |  |
Canceled/Forfeited | (101,599) |  |  | 37.64 |  |  |  |  |
Outstanding, March 31, 2026 | 2,327,465 |  |  | $ | 15.67 |  |  | 7.40 |  | $ | — |
Exercisable at March 31, 2026 | 1,164,823 |  |  | $ | 28.71 |  |  | 6.02 |  | $ | — |
Vested and unvested expected to vest at March 31, 2026 | 2,327,465 |  |  | $ | 15.67 |  |  | 7.40 |  | $ | — |
Schedule of Valuation Assumptions Used to Calculate Fair Value of Employee Options Awarded | The weighted average grant date fair value of the stock options granted during the three months ended March 31, 2025 was $2.67 and was calculated using the following estimated assumptions under the Black-Scholes option pricing model:
|  |  | Three Months Ended March 31,
|  |  | 2025
Expected term (years) |  |  | 6.0
Risk free interest rate |  |  | 4.4%
Expected volatility |  |  | 113%
Expected dividends |  |  | None
Schedule of Restricted Stock Awards | The following table presents a summary of RSUs under the 2010 Plan as of March 31, 2026:
| Number of Shares |  | Weighted Average Grant Date Fair Value
Unvested, December 31, 2025 | 257,400 |  |  | $ | 3.13 |
Awarded | — |  |  | — |
Vested | (64,350) |  |  | 3.13 |
Forfeited | (44,700) |  |  | 3.13 |
Unvested, March 31, 2026 | 148,350 |  |  | $ | 3.13 |
Schedule of Stock-Based Compensation Expense | For the three months ended March 31, 2026 and 2025, the Company recorded stock-based compensation expense to the following line items in its costs and expenses section of the Condensed Consolidated Statements of Operations and Comprehensive Loss:
| Three Months Ended March 31, |  |
(in thousands) | 2026 |  | 2025 |  |  |  |
Research and development | $ | 229 |  |  | $ | 592 |  |  |  |  |
General and administrative | 346 |  |  | 572 |  |  |  |  |
Total stock-based compensation expense | $ | 575 |  |  | $ | 1,164 |  |  |  |  |

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- Definition Tabular disclosure of the changes in outstanding nonvested restricted stock shares. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Subparagraph (c) -Paragraph 2 -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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