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Share-Based Compensation (Tables)

9 Months Ended

12 Months Ended

Sep. 30, 2025

Dec. 31, 2024

Share-Based Compensation [Abstract]

Schedule of Company’s Stock Option Activity

The summary of the Company’s stock option activity is as follows:  

		Number of Stock Options				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Life
Outstanding at December 31, 2024			329,395			$	51.30				5.4
Granted			8,080				9.60				10
Exercised			-				-				-
Forfeited/Expired/Cancelled			(114,840	)			50.39				-
Outstanding at September 30, 2025			222,635			$	50.28				4.4
Exercisable at  September 30, 2025			180,146			$	51.85				4.4

The summary of the Company’s stock option activity is as follows:

		Number of Stock Options				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Life
Outstanding at December 31, 2023			369,092			$	49.20				6.1
Granted			-				-				-
Exercised			-				-				-
Forfeited/Expired/Cancelled			(39,698	)		$	30.90				-
Outstanding at December 31, 2024			329,395			$	51.30				5.4
Exercisable at December 31, 2024			276,060			$	51.30				5.4

Schedule of Company’s Restricted Stock Unit Activity

The summary of the Company’s restricted stock unit activity is as follows:  

						Weighted- Average				Weighted- Average
		Number of				Grant Date				Remaining
		Shares				Fair Value				Vesting Period
Unvested at December 31, 2024			739			$	48.90				0.2
Granted			16,667				9.60				2.6
Vested			(142	)			48.90				—
Forfeited/Expired/Cancelled			(597	)			48.90				—
Unvested at September 30, 2025			16,667			$	9.60				2.4

The summary of the Company’s restricted stock unit activity is as follows:

		Number of Shares				Weighted-Average Grant Date Fair Value				Weighted-Average Remaining Vesting Period
Outstanding at December 31, 2023			3,124			$	48.90				1.2
Granted			—				—				—
Vested			(2,386	)			48.90				—
Forfeited			—				—				—
Outstanding at December 31, 2024			738			$	48.90				0.2

Schedule of Recorded Stock-Based Compensation Expense

The summary of the recorded stock-based compensation expense is as follows:

		Three Months Ended September 30,								Nine Months Ended September 30,
		2025				2024				2025				2024
Research and development		$	4			$	11			$	22			$	62
General and administrative			282				404				1,136				1,469
Total stock-based compensation		$	286			$	415			$	1,158			$	1,531

The summary of the recorded stock-based compensation expense is as follows:

		Years ended December 31,
		2024				2023
Research and development		$	72			$	118
General and administrative			1,855				2,187
Total stock-based compensation		$	1,927			$	2,305

Schedule of Fair Value Assumptions of the Stock Options Granted to Employees, Directors and Nonemployees

The assumptions that the Company used to determine the fair value of the stock options granted to employees, directors and nonemployees were as follows:

		Year ended December 31, 2023
Risk-free interest rate			3.53	%
Expected term (in years)			6.3
Expected volatility			71	%
Expected dividend yield			0	%

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)
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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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