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Common Stock, Stock Options and Warrants - Schedule of Exercise of Outstanding Warrants (Details)	Dec. 31, 2024 $ / shares shares
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 3.91
Number | shares	3,458,937
August 2018 Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 28.75
Number | shares	156,863
Expiration Date	Aug. 14, 2025
August 2018 Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 39.84
Number | shares	7,576
Expiration Date	Aug. 08, 2025
April 2019 Registered Direct/Private Placement Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 35.5
Number | shares	51,780
Expiration Date	Apr. 05, 2025
April 2019 Registered Direct/Private Placement Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 48.28
Number | shares	9,605
Expiration Date	Apr. 05, 2025
September 2019 Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 19.25
Number | shares	111,732
Expiration Date	Sep. 27, 2025
September 2019 Offering Underwriter [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 27.97
Number | shares	7,774
Expiration Date	Sep. 27, 2025
February 2020 Exercise Agreement Placement Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 31.88
Number | shares	5,555
Expiration Date	Aug. 19, 2025
May 2020 Registered Direct Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 25
Number | shares	66,824
Expiration Date	Nov. 18, 2025
May 2020 Registered Direct Offering Placement Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 33.2
Number | shares	6,226
Expiration Date	May 14, 2025
August 2020 Underwriter [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 32.81
Number | shares	8,079
Expiration Date	Aug. 10, 2025
January 2021 Registered Direct Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 30.78
Number | shares	123,648
Expiration Date	Jul. 27, 2026
January 2021 Registered Direct Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 40.44
Number | shares	14,065
Expiration Date	Jul. 27, 2026
February 2021 Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 42.5
Number | shares	823,211
Expiration Date	Feb. 19, 2026
February 2021 Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 47.03
Number | shares	100,256
Expiration Date	Feb. 19, 2026
May 2023 Registered Direct Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 37.5
Number | shares	500,000
Expiration Date	May 08, 2028
May 2023 Registered Direct Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 37.5
Number | shares	35,000
Expiration Date	May 03, 2028
April 2024 Registered Direct Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 18.75
Number | shares	857,143
Expiration Date	Oct. 30, 2029
April 2024 Registered Direct Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 21.875
Number | shares	60,000
Expiration Date	Apr. 25, 2029
November 2024 Offering Investors [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 6.25
Number | shares	480,000
Expiration Date	Nov. 18, 2029
November 2024 Offering Agent [Member]
Schedule of Exercise of Outstanding Warrants [Line Items]
Exercise price (in Dollars per share) | $ / shares	$ 7.8125
Number | shares	33,600
Expiration Date	Nov. 15, 2029

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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