-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 ElCIMHst7n22JsmKSSroSg==

<SEC-DOCUMENT>0000929638-07-000685.txt : 20071120
<SEC-HEADER>0000929638-07-000685.hdr.sgml : 20071120
<ACCEPTANCE-DATETIME>20071120163831
ACCESSION NUMBER:		0000929638-07-000685
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071116
FILED AS OF DATE:		20071120
DATE AS OF CHANGE:		20071120

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HARVARD BIOSCIENCE INC
		CENTRAL INDEX KEY:			0001123494
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				043306140
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		84 OCTOBER HILL RD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746
		BUSINESS PHONE:		5088938999

	MAIL ADDRESS:	
		STREET 1:		84 OCTOBER HILL ROAD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HSO LIMITED PARTNERSHIP
		CENTRAL INDEX KEY:			0001332633
		STATE OF INCORPORATION:			E9
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-31923
		FILM NUMBER:		071260135

	BUSINESS ADDRESS:	
		STREET 1:		THE CAYMAN CORPORATE CENTRE, 4TH FLOOR
		STREET 2:		27 HOSPITAL ROAD
		CITY:			GEORGETOWN, GRAND CAYMAN
		STATE:			E9
		ZIP:			00000
		BUSINESS PHONE:		345-945-1400

	MAIL ADDRESS:	
		STREET 1:		THE CAYMAN CORPORATE CENTRE, 4TH FLOOR
		STREET 2:		27 HOSPITAL ROAD
		CITY:			GEORGETOWN, GRAND CAYMAN
		STATE:			E9
		ZIP:			00000

	FORMER NAME:	
		FORMER CONFORMED NAME:	Highbridge Strategic Opportunities LP
		DATE OF NAME CHANGE:	20050708
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>frm4hso11202007_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2007-11-16</periodOfReport>

    <dateOfOriginalSubmission>2007-11-19</dateOfOriginalSubmission>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001123494</issuerCik>
        <issuerName>HARVARD BIOSCIENCE INC</issuerName>
        <issuerTradingSymbol>HBIO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001332633</rptOwnerCik>
            <rptOwnerName>HSO LIMITED PARTNERSHIP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>THE CAYMAN CORPORATE CENTRE, 4TH FLOOR</rptOwnerStreet1>
            <rptOwnerStreet2>27 HOSPITAL ROAD</rptOwnerStreet2>
            <rptOwnerCity>GEORGETOWN, GRAND CAYMAN</rptOwnerCity>
            <rptOwnerState>E9</rptOwnerState>
            <rptOwnerZipCode>00000</rptOwnerZipCode>
            <rptOwnerStateDescription>CAYMAN ISLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-11-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>6210</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.8999</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3467718</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-11-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>7612</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.8988</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3475330</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-11-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4567</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.9063</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3479897</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-11-19</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
                <footnoteId id="F2"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>5043</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.741</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3484940</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This amendment is being filed in order amend four line-items by correcting (a) a typographical error included in one
 line-item as to the number of shares purchased and (b) making corresponding revisions to the total amounts listed in column
 5 of each of the four line-items based on such corrected number of shares purchased.</footnote>
        <footnote id="F2">The reporting person's purchase of HBIO common stock reported herein was matchable under Section 16(b) of the Securities
 Exchange Act of 1934, as amended, to the extent of 100 shares, with the reporting person's sale of 100 shares of HBIO common
 stock on September 25, 2007 (the &quot;Sale&quot;). The reporting person has agreed to pay to HBIO the full amount of the profit
 realized in connection with the short-swing transactions, less transaction costs, and less amounts previously paid to HBIO
 by the reporting person in connection with the Sale and a previously disclosed transaction matchable against the Sale.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/HSO Limited Partnership, by Skystone Advisors LLC, Investment Member of the General Partner, by Kerry Nelson, Managing Member</signatureName>
        <signatureDate>2007-11-20</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
