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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001181431-09-026919.txt : 20090526
<SEC-HEADER>0001181431-09-026919.hdr.sgml : 20090525
<ACCEPTANCE-DATETIME>20090526161242
ACCESSION NUMBER:		0001181431-09-026919
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20090521
FILED AS OF DATE:		20090526
DATE AS OF CHANGE:		20090526

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HARTE NEAL J
		CENTRAL INDEX KEY:			0001281069

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33957
		FILM NUMBER:		09852045

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HARVARD BIOSCIENCE INC
		CENTRAL INDEX KEY:			0001123494
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				043306140
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		84 OCTOBER HILL RD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746
		BUSINESS PHONE:		5088938999

	MAIL ADDRESS:	
		STREET 1:		84 OCTOBER HILL ROAD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd243831.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-05-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001123494</issuerCik>
        <issuerName>HARVARD BIOSCIENCE INC</issuerName>
        <issuerTradingSymbol>HBIO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001281069</rptOwnerCik>
            <rptOwnerName>HARTE NEAL J</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>6 EVERETT AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>WINCHESTER</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01890</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Non-qualified Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.18</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2009-05-21</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>18000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.18</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2019-05-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, par value $0.01 per share</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>18000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>18000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The shares vest in three equal installments on May 21, 2010, 2011 and 2012.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Thomas McNaughton, Attorney in Fact</signatureName>
        <signatureDate>2009-05-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24.
<SEQUENCE>2
<FILENAME>rrd218606_246679.htm
<DESCRIPTION>POWER OF ATTORNEY
<TEXT>
<HTML>
<HEAD>
<TITLE>_</TITLE>
</HEAD>
<BODY>
<B><FONT SIZE=3><P ALIGN="CENTER">LIMITED POWER OF ATTORNEY</P>
<P ALIGN="CENTER">FOR </P>
<P ALIGN="CENTER">HARVARD BIOSCIENCE, INC.</P>
<U><P ALIGN="CENTER">SECTION 16(a) FILINGS</P>
</B></U>
<P>&#9;Know all by these presents, that the undersigned hereby revokes all previous Powers of Attorney executed by the undersigned with respect to the matters set forth below, and hereby constitutes and appoints each of Chane Graziano, David Green and Thomas McNaughton, signing singly, the undersigned's true and lawful attorney-in-fact to:</P>
<DIR>
<DIR>
<DIR>
<DIR>
<P>&#9;(1)&#9;execute for and on behalf of the undersigned, in the undersigned's capacity as an officer, director and/or stockholder of Harvard Bioscience, Inc. (&quot;the Company"), Forms&nbsp;3, 4, and 5 and amendments thereto in accordance with Section&nbsp;16(a) of the Securities Exchange Act of 1934, as amended, and the rules thereunder; </P>
<P>&#9;(2)&#9;do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form&nbsp;3, 4, or 5 or amendment thereto and timely file such form with the United States Securities and Exchange Commission (the "SEC") and any stock exchange or similar authority; and</P>
<P>&#9;(3)&#9;take any other action of any type whatsoever which, in the opinion of such attorney-in-fact, may be necessary or desirable in connection with the foregoing authority, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve.</P>
</DIR>
</DIR>
</DIR>
</DIR>
<P>&#9;The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this Power of Attorney and the rights and powers herein granted.  The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to comply with Section&nbsp;16 of the Securities Exchange Act of 1934.</P>
<P>&#9;This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms&nbsp;3, 4, and 5 with respect to the undersigned's holdings of and transactions in securities of the Company, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact.  This Power of Attorney may be filed with the SEC as a confirming statement of the authority granted herein.</P>
<P>&#9;IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this <U>3<SUP>rd</SUP> </U>day of December, 2008.</P>
<P>&nbsp;</P>
<P>&nbsp;</P>
<P>&#9;<U>/s/ Neal Harte&#9;&#9;</P>
</U><P>&#9;Name:&#9;Neal Harte </P></FONT></BODY>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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