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Note 13 - Litigation Settlement (Details Textual) - USD ($)		3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 10, 2022	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021	Mar. 31, 2022
Litigation Settlement, Expense		$ (4,880,000)	$ 0	$ 311,000	$ 0
Series E Preferred Stock in Biostage [Member]
Equity Securities without Readily Determinable Fair Value, Amount		$ 3,900,000		$ 3,900,000
Convertible Preferred Stock [Member] | Biostage [Member]
Preferred Stock, Dividend Rate, Percentage				8.00%
Preferred Stock, Par or Stated Value Per Share (in dollars per share)		$ 1,000		$ 1,000
Preferred Stock, Mandatory Conversion, Minimum Qualified Offering Amount		$ 4,000,000		$ 4,000,000
Case in Suffolk Superior Court [Member]
Loss Contingency, Estimate of Possible Loss							$ 5,200,000
Legal Fees						$ 300,000
Litigation Settlement, Expense		(4,900,000)
Case in Suffolk Superior Court [Member] | Convertible Preferred Stock [Member]
Stock Issued During Period, Shares, Issued For Settlement (in shares)	4,000
Stock Issued During Period, Value, Issued for Settlement	$ 4,000,000.0
Estimated Litigation Liability		$ 500,000		$ 500,000

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Amount of investment in equity security without readily determinable fair value.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 321
-SubTopic 10
-Section 50
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The amount of expense provided in the period for legal costs incurred on or before the balance sheet date pertaining to resolved, pending or threatened litigation, including arbitration and mediation proceedings.

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-SubTopic 10
-Section S99
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-Topic 450
-SubTopic 20
-Section 50
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