<SEC-DOCUMENT>0001171843-22-003861.txt : 20220520
<SEC-HEADER>0001171843-22-003861.hdr.sgml : 20220520
<ACCEPTANCE-DATETIME>20220520161551
ACCESSION NUMBER:		0001171843-22-003861
CONFORMED SUBMISSION TYPE:	SD
PUBLIC DOCUMENT COUNT:		2
<RULE>
<RULE-NAME>13p-1
<ITEM>
<ITEM-NUMBER>1.01
<ITEM-PERIOD>20211231
</ITEM>
<ITEM>
<ITEM-NUMBER>1.02
<ITEM-PERIOD>20211231
</ITEM>
</RULE>
FILED AS OF DATE:		20220520
DATE AS OF CHANGE:		20220520

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HARVARD BIOSCIENCE INC
		CENTRAL INDEX KEY:			0001123494
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				043306140
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SD
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33957
		FILM NUMBER:		22947791

	BUSINESS ADDRESS:	
		STREET 1:		84 OCTOBER HILL RD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746
		BUSINESS PHONE:		5088938999

	MAIL ADDRESS:	
		STREET 1:		84 OCTOBER HILL ROAD
		CITY:			HOLLISTON
		STATE:			MA
		ZIP:			01746
</SEC-HEADER>
<DOCUMENT>
<TYPE>SD
<SEQUENCE>1
<FILENAME>sd_051822.htm
<DESCRIPTION>FORM SD
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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">UNITED STATES</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">SECURITIES AND EXCHANGE COMMISSION</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">Washington, D.C. 20549</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM SD</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SPECIALIZED DISCLOSURE REPORT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Harvard Bioscience, Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact name of the registrant as specified in its
charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>DELAWARE</B></FONT></TD>
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>001-33957</B></FONT></TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>04-3306140</B></FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(State or Other Jurisdiction of</FONT></TD>
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Commission File Number)</FONT></TD>
    <TD STYLE="padding-left: 18.5pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(IRS Employer Identification Number)</FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt; width: 33%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Incorporation)</FONT></TD>
    <TD STYLE="text-align: center; width: 34%">&nbsp;</TD>
    <TD STYLE="text-align: center; width: 33%">&nbsp;</TD></TR>
</TABLE>

<P STYLE="margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt; width: 33%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>84 October Hill Road, Holliston, MA</B></FONT></TD>
    <TD STYLE="text-align: center; width: 34%">&nbsp;</TD>
    <TD STYLE="text-align: center; width: 33%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>01746</B></FONT></TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="text-align: center; padding-left: 0pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Address of Principal Executive Offices)</FONT></TD>
    <TD STYLE="text-align: center">&nbsp;</TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Zip Code)</FONT></TD></TR>
</TABLE>

<P STYLE="margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 25%">&nbsp;</TD>
    <TD STYLE="text-align: center; padding-left: 0pt; width: 25%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Michael A. Rossi</B></FONT></TD>
    <TD STYLE="text-align: center; padding-left: 0pt; width: 25%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>(508) 893-8999</B></FONT></TD>
    <TD STYLE="text-align: center; width: 25%">&nbsp;</TD></TR>
  </TABLE>
<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">(Name and telephone number, including area code, of the person
to contact in connection with this report.)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 3pt 0pt 0">Check the appropriate box to indicate the rule pursuant to
which this form is being filed, and provide the period to which the information in this form applies:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 23pt">&#9746; Rule 13p-1 under the Securities Exchange Act (17 CFR
240.13p-1) for the reporting period from January 1 to December 31, 2021.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 23pt"><FONT STYLE="font-family: Wingdings"></FONT>&#9744; <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Rule
13q-1 under the Securities Exchange Act (17 CFR 240.13q-1) for the fiscal year ended December&nbsp;31, 2021.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 23pt"><FONT STYLE="font-size: 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif"></FONT></FONT></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0 0pt 23pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">&nbsp;</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Section 1 - Conflict Minerals Disclosure</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 1.01 Conflict Minerals Disclosure and Report</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Conflict Minerals Disclosure</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><BR>
This Form&nbsp;SD of Harvard Bioscience, Inc. is filed pursuant to Rule&nbsp;13p-1 promulgated under the Securities Exchange Act of 1934,
as amended, for the reporting period January&nbsp;1, 2021 to December&nbsp;31, 2021.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 41pt 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 41pt 0pt 0">A copy of Harvard Bioscience Inc.&rsquo;s Conflict Minerals
Report is filed as Exhibit 1.01 hereto and is publicly available at: http://investor.harvardbioscience.com/corporate-governance.cfm. The
content of any website referred to in this Form SD is included for general information only and is not incorporated by reference in this
Form SD or the Conflict Mineral Report.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 1.02 Exhibit</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Harvard Bioscience, Inc. is hereby filing its Conflict Minerals Report
as Exhibit 1.01 to this Form SD.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Section 3 &ndash; Exhibits</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Item 3.01 Exhibits</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The following exhibit is filed as part of this report.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P><TABLE CELLPADDING="0" CELLSPACING="0" STYLE="border-collapse: collapse; width: 100%; font: 10pt Times New Roman, Times, Serif">
  <TR STYLE="vertical-align: bottom; background-color: White">
    <TD STYLE="width: 8%; color: #0000EE; padding-bottom: 1pt"><A HREF="exh_101.htm">Exhibit 1.01</A></TD>
    <TD STYLE="width: 92%; color: #0000EE; text-align: left; padding-bottom: 1pt"><A HREF="exh_101.htm">Conflict Minerals Report as required
    by Items 1.01 and 1.02 of this Form SD</A></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; color: Red"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; color: Red"><B>&nbsp;</B></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; color: Red"><B></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; color: Red"><B></B></P>

<P STYLE="text-align: center; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the duly authorized undersigned.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><U>Harvard Bioscience, Inc.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">(Registrant)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: bottom">
    <TD STYLE="width: 33%; border-bottom: Black 1pt solid; padding-left: 2pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/ Michael A. Rossi</FONT></TD>
    <TD STYLE="width: 27%; border-bottom: Black 1pt solid; padding-left: 42pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">May 20, 2022</FONT></TD>
    <TD STYLE="width: 40%">&nbsp;</TD></TR>
  <TR STYLE="vertical-align: bottom">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By: Michael A. Rossi, Chief Financial Officer</FONT></TD>
    <TD>&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  </TABLE>

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<TYPE>EX-1.01
<SEQUENCE>2
<FILENAME>exh_101.htm
<DESCRIPTION>EXHIBIT 1.01
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<P STYLE="text-align: right; font: 10pt Times New Roman, Times, Serif; margin: 0pt"><B>Exhibit 1.01</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Harvard Bioscience, Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Conflict Minerals Report</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>For the Year Ended December 31, 2021</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Forward Looking Statements</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><I>Forward-looking statements contained in this
Report are made based on known events and circumstances at the time of release, and as such, are subject in the future to unforeseen uncertainties
and risks. Statements in this Report which express a belief, expectation, or intention, as well as those that are not historical fact,
are forward-looking statements, including statements related to the Company&rsquo;s compliance efforts and expected actions identified
in this Report. These forward-looking statements are subject to various risks, uncertainties and assumptions, including, among other matters,
the Company&rsquo;s customers&rsquo; requirements to use certain suppliers, the Company&rsquo;s suppliers&rsquo; responsiveness and cooperation
with the Company&rsquo;s due diligence efforts, the Company&rsquo;s ability to implement improvements in its conflict minerals program
and the Company&rsquo;s ability to identify and mitigate related risks in its supply chain. If one or more of these or other risks materialize,
actual results may vary materially from those expressed. For a more complete discussion of these and other risk factors, see the Company&rsquo;s
other filings with the Securities and Exchange Commission (&ldquo;SEC&rdquo;), including its Annual Report on Form 10-K for the year ended
December 31, 2021 and subsequent Quarterly Reports on Form 10-Q. The Company makes these statements as of the date of this disclosure,
and undertakes no obligation to update them unless otherwise required by law.</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>Conflict Minerals Disclosure</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">This report for the year ended December
31, 2021 is presented to comply with Rule 13p-1 under the Securities Exchange Act of 1934, as amended (the &ldquo;Rule&rdquo;). The SEC
adopted the Rule to implement reporting and disclosure requirements related to conflict minerals as directed by Section 1502 of the Dodd-Frank
Wall Street Reform and Consumer Protection Act of 2010 (the &ldquo;Section 1502 of the Dodd-Frank Act&rdquo;). The Rule imposes certain
reporting obligations on SEC registrants whose manufactured products contain conflict minerals which are necessary to the functionality
or production of their products (herein referred to as &ldquo;Covered Products&rdquo;). Conflict Minerals are defined as cassiterite,
columbite-tantalite, gold, wolframite, and their derivatives, which are limited to tin, tantalum, tungsten, and gold (&ldquo;Conflict
Minerals&rdquo; or &ldquo;3TGs&rdquo;) for the purposes of this report. These requirements apply to registrants whatever the geographic
origin of the Conflict Minerals and whether or not they fund armed conflict.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">As described in this report, Harvard Bioscience,
Inc., a Delaware corporation (herein referred to as &ldquo;Harvard Bioscience,&rdquo; the &ldquo;Company,&rdquo; &ldquo;we,&rdquo; &ldquo;us,&rdquo;
or &ldquo;our&rdquo;), has reason to believe that some of the Conflict Minerals present in its supply chain may have originated in the
Covered Countries and therefore performed due diligence on the source and chain of custody of the 3TGs in question to determine whether
its products are &ldquo;DRC Conflict Free.&rdquo; Based on such determination, Harvard Bioscience conducted a reasonable country of origin
inquiry (&ldquo;RCOI&rdquo;) that was reasonably designed to determine whether any of the Conflict Minerals in the Covered Products originated
in the Democratic Republic of the Congo or an adjoining country or were from recycled or scrap sources. The Company designed its due diligence
measures to conform, in all material respects, with the internationally recognized due diligence framework in The Organisation for Economic
Co-Operation and Development (&ldquo;OECD&rdquo;) Due Diligence Guidance for Responsible Supply Chains of Minerals from Conflict-Affected
and High-Risk Areas and the related supplements for gold, tin, tantalum and tungsten (the &ldquo;OECD Guidance&rdquo;).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Following the RCOI, Harvard Bioscience
exercised due diligence on the source and chain of custody of the applicable Conflict Minerals. Information on the RCOI, steps the Company
has taken to exercise due diligence on the source and chain of custody of any Conflict Minerals in the Covered Products and the results
of this due diligence are described in this report.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">For purposes of this report, &ldquo;Covered
Countries&rdquo; refers to the Democratic Republic of the Congo (the &ldquo;DRC&rdquo;) and adjoining countries, defined as any country
that shares an internationally recognized border with the Democratic Republic of the Congo. The Company is unable with absolute assurance
to determine the origin of the Conflict Minerals in our products and therefore cannot exclude the possibility that some may have originated
in the Covered Countries.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><U>1. Company Overview</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">This report has been prepared by management
of Harvard Bioscience. The information includes the activities of all majority-owned subsidiaries as of December 31, 2021.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Harvard Bioscience is a leading developer,
manufacturer and seller of technologies, products and services that enable fundamental research, discovery, and preclinical testing for
drug development. The Company&rsquo;s customers range from renowned academic institutions and government laboratories, to the world&rsquo;s
leading pharmaceutical, biotechnology and contract research organizations. With operations in North America, Europe and China, the Company
sells through a combination of direct and distribution channels to customers around the world.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>Conflict Minerals Policy</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">The Company adopted a conflict minerals policy
in 2013 articulating the Conflict Minerals supply chain due diligence process and the Company&rsquo;s commitments to reporting obligations
regarding Conflict Minerals. See the Company&rsquo;s policy on its website: Harvard Bioscience, Inc.'s Conflicts Mineral Policy.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><U>2. Product Description</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0.25in 0pt 0">As of December 31, 2021, our broad core product range was
organized into two commercial product families: Preclinical devices and instruments and Cellular and Molecular technologies. As of December
31, 2021, the Company primarily sold our products under brand names, including Harvard Apparatus, DSI (Data Scientific), Biochrom, Buxco,
BTX, and MCS. Our products consist of instruments, consumables, and systems made up of several individual products. The Company manufactures
its products at its locations in the United States, Germany, Sweden and Spain. The Company&rsquo;s broad and complex product range may
contain Conflict Minerals within the following components:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 11.65pt"></TD><TD STYLE="width: 6.35pt">&middot;</TD><TD>Tantalum, used in capacitors,</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 11.65pt"></TD><TD STYLE="width: 6.35pt">&middot;</TD><TD>Tin, used in soldered components,</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 11.65pt"></TD><TD STYLE="width: 6.35pt">&middot;</TD><TD>Tungsten, used in coatings, alloys, heating elements and electrodes, and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 11.65pt"></TD><TD STYLE="width: 6.35pt">&middot;</TD><TD>Gold, used in circuit boards, electrodes and electronic components.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.4pt"></TD><TD STYLE="width: 8.6pt"><B>3.</B></TD><TD><B><U>Description of Reasonable Country of Origin Inquiry, or RCOI</U></B></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The Company began its RCOI by completing a supplier list extraction
from our Vendor List. This list was then filtered to remove:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.4pt"></TD><TD STYLE="width: 17.6pt">&bull;</TD><TD>Service Providers/Suppliers</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.4pt"></TD><TD STYLE="width: 17.6pt">&bull;</TD><TD>Indirect Materials Suppliers</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.4pt"></TD><TD STYLE="width: 17.6pt">&bull;</TD><TD>Inactive Suppliers (minimum 2 years since last purchase)</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">This ensures that all suppliers surveyed
provided items to Harvard Bioscience that were used in final products in the year 2021. Once the filtering was completed, the Company
populated the list with contact information and this list was then provided to Assent Compliance (&ldquo;Assent&rdquo;), our third-party
service provider, for upload to their Assent Compliance Manager SaaS system (&ldquo;ACM&rdquo;). It was deemed appropriate to not further
filter this list based on the necessity of the presence of Conflict Minerals in the products as the Company could not definitively determine
the presence or absence of Conflict Minerals in all parts supplied. The survey employed the Responsible Minerals Initiative (&ldquo;RMI&rdquo;)
Conflict Minerals Reporting Template (the &ldquo;CMRT&rdquo;), version 6.0 or higher, originally developed by the Responsible Business
Alliance (&ldquo;RBA&rdquo;) and The Global e-Sustainability Initiative. The CMRT allows for further scoping as they ask suppliers whether
any of the Conflict Minerals are intentionally added and if they are necessary to the functionality or production of their products. Assent
conducted additional analysis of the supply chain and such analysis combined with supplier feedback, allowed Assent and Harvard Bioscience
to remove additional suppliers from scope of the conflict minerals regulation.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Assent then conducted the supplier survey
portion of the RCOI. During the supplier survey, suppliers were contacted via the ACM, a SaaS platform that enables its users to complete
and track supplier communications as well as allow suppliers to upload completed CMRTs directly to the platform for assessment and management.
Non-responsive suppliers were contacted a minimum of three times by ACM and then were also managed by the Assent Compliance team in one-on-one
communications. This includes two to three direct follow ups from that team. Assent&rsquo;s communications with suppliers included training
and education on the completion of the CMRT to alleviate any remaining confusion with suppliers. All of these communications were monitored
and tracked in Assent's system for future reporting and transparency.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The program continues to include automated
data validation on all submitted CMRTs. The goal of data validation is to increase the accuracy of submissions and identify any contradictory
answers in the CMRT. This data validation is based on questions within the declaration tab of the CMRT which helps to identify areas that
require further classification or risk assessment, as well as understand the due diligence efforts of suppliers. The results of this data
validation contribute to the program&rsquo;s health assessment and are shared with suppliers to ensure they understand areas that require
clarification or improvement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">All submitted declaration forms are accepted
so that data is retained, but they are classified as valid or invalid based on a set criteria of validation errors. Suppliers are contacted
regarding invalid forms and are encouraged to submit a valid form. Suppliers are also provided with guidance on how to correct these validation
errors in the form of feedback to their CMRT submission, training courses and direct engagement help through Assent&rsquo;s multilingual
Supplier Experience team. Since some suppliers may remain unresponsive to feedback, the Company tracks program gaps to account for future
improvement opportunities As of May 11, 2022, there were 14 invalid supplier submissions that could not be corrected.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">As of May 11, 2022, there were 668 suppliers
in scope of the conflict minerals program and 462 (or 69%) provided a completed CMRT.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Assent compared the list of smelters
and refiners provided in our suppliers&rsquo; responses to the lists of smelters maintained by the RMI and, if a supplier indicated that
a facility was certified as conflict-free, confirmed that the facility was listed on RMI&rsquo;s list of validated conflict free smelters
and refiners of 3TGs. Our suppliers identified a total of 335 smelters and refiners that appear on the lists maintained by RMI. Of these
335 smelters and refiners, 231 are validated as conflict free by RMI or a cross-recognized initiative, and, based on information provided
by RMI, a further 18 have agreed to undergo or are currently undergoing a third-party audit. Most of the CMRTs the Company received were
made on a company- or division-level basis which did not allow the Company to identify which smelters or refiners listed by its suppliers
actually processed the 3TGs contained in our products. Based on the RCOI, the Company had reason to believe that some of the 3TGs may
have originated from the Covered Countries, therefore, in accordance with the Rule, performed due diligence on the source and chain of
custody of the Conflict Minerals in question.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><U>4. Due Diligence Process</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.1 Design of Due Diligence</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company designed its due diligence
measures to conform, in all material respects, with the framework in the OECD Guidance and the related supplements. The program aligns
with the five steps for due diligence that are described by the OECD Guidance and the Company continues to evaluate market expectations
for data collection and reporting to achieve continuous improvement opportunities.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company developed its due diligence
process to address each of these five steps, namely:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18.6pt"></TD><TD STYLE="width: 8.4pt">1.</TD><TD>Establishing strong company management systems regarding conflict minerals;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18.6pt"></TD><TD STYLE="width: 8.4pt">2.</TD><TD>Identifying and assessing risks in our supply chain;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18.6pt"></TD><TD STYLE="width: 8.4pt">3.</TD><TD>Designing and implementing a strategy to respond to identified risks in our supply chain;</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18.6pt"></TD><TD STYLE="width: 8.4pt">4.</TD><TD>Utilizing independent third-party audits of supply chain diligence; and</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 18.6pt"></TD><TD STYLE="width: 8.4pt">5.</TD><TD>Publicly reporting on our supply chain due diligence</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Due diligence requires the Company&rsquo;s
necessary reliance on data provided by direct suppliers and third-party audit programs. There is a risk of incomplete or inaccurate data
as the process cannot be fully owned by the Company. However, through active risk identification, risk assessment, as well as continued
outreach and process validation, risk gaps can be mitigated. This aligns with industry standards and market expectations for downstream
companies&rsquo; due diligence.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company is a downstream supplier,
many steps removed from the mining of 3TG. A large number of suppliers, through multiple tiers of distribution, supply the components
and materials integrated into our products. Furthermore, we do not purchase raw ore or unrefined conflict minerals or make purchases from
the Covered Countries. The origin of the Conflict Minerals cannot be determined with any certainty once the raw ores are smelted, refined
and converted to ingots, bullion or other Conflict Mineral containing derivatives. The smelters and refiners consolidate raw ore and represent
the best actors in the total supply chain to possess knowledge of the origin of the ores they procure.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The OECD Guidance specifies that the requirements
for compliance should reflect a company&rsquo;s position in the supply chain. In particular, the OECD Guidance states that the implementation
of due diligence should be tailored to a company&rsquo;s activities and relationships and that the nature and extent of due diligence
may vary based on a company&rsquo;s size, products, relationships with suppliers and other factors. Due to practical difficulties associated
with supply chain complexities, the OECD Guidance advises that downstream companies exercise due diligence primarily by establishing controls
over their immediate suppliers. Accordingly, we rely primarily on our &ldquo;tier 1&rdquo; (direct) suppliers to provide information with
respect to the origin of the Conflict Minerals contained in the components and materials supplied to us.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.2 Management Systems</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Internal Compliance Team</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Harvard Bioscience has established a cross-functional
Conflict Minerals Compliance Team led by the Company&rsquo;s head of global engineering. The Conflict Minerals Compliance Team is responsible
for implementing the conflict minerals compliance strategy and briefing senior management about the results of these due diligence efforts.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company also uses a third-party service
provider, Assent, to assist with evaluating supply chain information regarding 3TGs, identifying potential risks, and in the development
and implementation of additional due diligence steps that the Company will undertake with suppliers in regard to Conflict Minerals.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company leverages Assent&rsquo;s Managed
Services in order to work with dedicated program specialists who support Harvard Bioscience&rsquo;s conflict minerals program. The Company
communicates regularly with the Assent team in order to receive updates on program status. Each member of Assent&rsquo;s Customer Success
team is trained in conflict minerals compliance and understands the intricacies of the CMRT and conflict minerals reporting, as well as
Section 1502 of the Dodd-Frank Act</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Control Systems</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">As the Company does not typically have
a direct relationship with Conflict Minerals smelters and refiners, the Company is engaged and actively cooperate with other major manufacturers
in our sector and other sectors. Controls include, but are not limited to, the use of the CMRT as the data collection format for our suppliers,
and our Code of Business Conduct and Ethics which outlines certain expected behaviors for all Harvard Bioscience employees. In addition,
the Company relies on its direct suppliers to provide information on the origin of the Conflict Minerals contained in components and materials
supplied to us, including sources of Conflict Minerals that are supplied to them from lower tier suppliers.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Supplier Engagement</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">With respect to the OECD requirement to strengthen engagement with
suppliers, the Company has, through Assent, provided education on the Conflict Minerals regulation as well as the expectations of the
law and for a continued business relationship. The Company puts a strong emphasis on supplier education and training. To accomplish this,
Assent&rsquo;s online resources are leveraged, and all in-scope suppliers have been provided with access to their library of conflict
minerals training and support resources. Also, Assent&rsquo;s automated feedback process that notifies suppliers of risks associated
with their CMRT submission serves to educate suppliers of certain conflict minerals&rsquo; risks.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Grievance Mechanism</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Various communication channels exist to
serve as grievance mechanisms for early-warning risk awareness. The Company has multiple longstanding grievance mechanisms whereby employees
(internal) and suppliers (external) can report violations of the Company&rsquo;s policies, including the Company&rsquo;s conflict minerals
policy. This includes but is not limited to the Company&rsquo;s whistleblower policies that are part of the Company&rsquo;s Code of Business
Conduct and Ethics located on the Company&rsquo;s website at http://investor.harvardbioscience.com/corporate-governance.cfm. Any violations
are reported to the Compliance Officer.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Violations or grievances at the industry
level can be reported to the RMI directly as well. This can be done at http://www.responsiblemineralsinitiative.org/responsible-minerals-assurance-process/grievance-mechanism/.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Maintain Records</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company has adopted a policy to retain
relevant documentation for a period of five years. Through Assent, a document retention policy to retain conflict minerals related documents,
including supplier responses to CMRTs and the sources identified within each reporting period, has been implemented. The Company stores
all of the information and findings from this process in a database that can be audited by internal or external parties.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.3 Identify and Assess Risk in the Supply Chain</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Because of the complexity of the Company&rsquo;s
products, and the depth, breadth, and constant evolution of the Company&rsquo;s supply chain, it is difficult to identify actors upstream
from the Company&rsquo;s direct suppliers.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Risks associated with supplier CMRT content
are identified automatically in the ACM based on criteria established for supplier responses. These risks are addressed by Assent staff
and members of the Company&rsquo;s internal Conflict Minerals Compliance Team, who contact the supplier, gather pertinent data and perform
an assessment of the supplier&rsquo;s Conflict Minerals status.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Risks at the supplier level may include
non-responsive suppliers or incomplete CMRTs or CMRTs that are submitted at the company level. In cases where a company-level CMRT (such
as when a company declares there are no 3TGs in any of its products) is submitted, the Company is unable to determine if all of the specified
smelters and refiners were used for 3TGs in the products supplied to the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Risks were identified by assessing the
due diligence practices and status of smelters and refiners identified in the supply chain by upstream suppliers that listed mineral processing
facilities on their CMRT declarations. Assent compared these facilities listed in the responses to the list of smelters and refiners consolidated
by the RMI to ensure that the facilities met the recognized definition of a 3TGs processing facility that was operational during the 2021
calendar year.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Assent determined if the smelter had been
audited against a standard in conformance with the OECD Guidance, such as the Responsible Minerals Assurance Process (&ldquo;RMAP&rdquo;).
The Company. does not have a direct relationship with smelters and refiners and does not perform direct audits of these entities within
their pre-supply chain. Smelters that are conformant to RMAP audit standards are considered to have their sourcing validated as &ldquo;conflict
free or responsibly sourced&rsquo;&rdquo;. In cases where the smelter/refiner&rsquo;s due diligence practices have not been audited against
the RMAP standard or they are considered non-conformant by RMAP, further due diligence steps are followed to notify suppliers reporting
these facilities. Smelters/refiners are actively monitored to proactively identify other risks pertaining to conflict minerals.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Each facility that meets the RMI definition
of a smelter or refiner of a 3TG mineral is assessed according to red-flag indicators defined in the OECD Guidance. Assent uses numerous
factors to determine the level of risk that each smelter poses to the supply chain by identifying red flags. These factors include:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Geographic proximity to Conflict-Affected
and High-Risk Areas.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Known mineral source country
of origin.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">RMAP audit status.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Credible evidence of unethical
or conflict sourcing.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Peer Assessments conducted
by credible third-party sources.</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 1pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Sanctions risks.</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Risk mitigation activities are initiated
whenever a supplier&rsquo;s CMRT reported facilities of concern. Through Assent, suppliers with submissions that included any smelters
of concern were immediately provided with feedback instructing that supplier to take their own independent risk mitigation actions. Examples
include the submission of a product specific CMRT to better identify the connection to products that they supply to in the Company. Additional
escalation may have been necessary to address any continued sourcing from these smelters of concern. Suppliers are given clear performance
objectives within reasonable timeframes with the ultimate goal of progressive elimination of these smelters of concern from the supply
chain.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">In addition, suppliers are guided to the
educational materials on mitigating the risks identified through the data collection process.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Suppliers are also evaluated on program
strength, which assists in making key risk mitigation decisions as the program progresses. The criteria used to evaluate the strength
of the program is based on certain questions in the CMRT related to the suppliers&rsquo; Conflict Minerals practices and policies.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify"></P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.4 Design and Implement a Strategy to Respond to Risks</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Together with Assent, the Company. developed
processes to assess and respond to the risks identified in the supply chain. The Company has a risk management plan, through which the
conflict minerals program is implemented, managed and monitored. As the program progresses, escalations are sent to non-responsive suppliers
to outline the importance of a response via CMRTs and to outline the required cooperation for compliance to the conflict minerals rules
and the Company&rsquo;s expectations.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Feedback on supplier submissions is given
directly to suppliers and educational resources are provided to assist suppliers in corrective action methods or to improve their internal
programs. In cases where suppliers have continuously been non-responsive or are not committed to corrective action plans, the Company
will assess if replacing that supplier is feasible. The results of the program and risk assessment are shared with the Company&rsquo;s
Conflict Minerals Compliance Team and senior management to ensure transparency within the Company.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.5 Carry out Independent Third-Party Audit of Supply Chain Due
Diligence at Identified Points in the Supply Chain</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company does not have a direct relationship
with any 3TG smelters/refiners and therefore do not perform or direct audits of these entities within the supply chain. Instead, we rely
on third-party audits of smelters/refiners conducted as part of the Responsible Minerals Assurance Process &ldquo;RMAP&rdquo;. The RMAP
uses independent private-sector auditors, and audits the source, including the mines of origin, and the chain of custody of the conflict
minerals used by smelters and refiners that agree to participate in the program.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">Assent directly engages smelters/refiners
that are not currently enrolled in the RMAP to encourage their participation and for those smelters/refiners already conformant to RMAP.
Assent thanks them for their efforts on behalf of its compliance partners. The Company is a signatory of these communications in accordance
with the requirements of downstream companies detailed in the OECD Guidance.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><I>4.6 Report Annually on Supply Chain Due Diligence</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">We report annually on our supply chain
due diligence by filing a Form SD and a Conflict Minerals Report with the SEC. Our Form SD and Conflict Minerals Report can be found on
the Corporate Governance page of our website: http://investor.harvardbioscience.com/corporate-governance.cfm. Information found on or
accessed through this website is not considered part of this report and is not incorporated by reference herein.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">This year the Company has also considered
impacts from the EU Conflict Minerals Regulation when disclosing details with regards to due diligence efforts. The Company will continue
to expand efforts both for transparency through the data collection process and risk evaluation, as well as the disclosure of efforts
through the form of public report.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

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<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 6.5in 0pt 0; text-indent: 0.4pt"><B>5. <U>Due Diligence </U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 6.5in 0pt 0; text-indent: 0.4pt"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 6.5in 0pt 0; text-indent: 0.4pt"><B>Results Survey</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 6.5in 0pt 0; text-indent: 0.4pt"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 6.5in 0pt 0; text-indent: 0.4pt"><B>Responses</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company actively surveys is supplier
chain. This year the Company surveyed 668 suppliers. Of those suppliers the Company received CMRTs from 462 suppliers. The Company reviews
the responses against criteria developed to determine whether further engagement with the suppliers is required. These criteria included
untimely or incomplete responses as well as inconsistencies within the data reported in the template. The Company, with the assistance
of Assent, has worked with these suppliers to provide revised responses. All final CMRT submissions were reviewed and validated to ensure
no inaccuracies or gaps in data were found. At the end of this process, 14 suppliers were unable to correct their CMRT and as such, are
still listed as invalid submissions.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Smelters or Refiners</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The information that the Company received
from a majority of its suppliers was at their company-wide level. Thus, the smelters or refiners identified by the suppliers may contain
smelters or refiners that processed Conflict Minerals that the suppliers supplied to their other customers, but not to the Company. As
a result, the Company is unable to conclusively determine whether such smelters or refiners were used to process the Conflict Minerals
necessary to the functionality or production of the Company&rsquo;s products during 2021. Because of this uncertainty, the Company is
also unable to conclusively determine whether each of the countries of origin identified in the due diligence process were the country
of origin of Conflict Minerals in the Company&rsquo;s products during 2021, and therefore also unable to conclusively determine the source
and chain of custody of those Conflict Minerals. In addition, the information that the Company receives from its suppliers may yield inaccurate
or incomplete information because they may not have received accurate and complete Conflict Minerals information from all the suppliers
in their own supply chain. As the Company is not a member of the RMI, the Company also does not have access to audit reports or detailed
findings of the third-party audits conducted as part of the RMI&rsquo;s RMAP or the LBMA Responsible Gold Program and, as a result, is
not responsible for the quality of these audits or the audit findings.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company&rsquo;s third-party service
provider compared the facilities listed in the responses in the CMRT to the list of smelters maintained by the RMI and confirmed that
the name was listed by RMI as a legitimate smelter. As of May 11, 2022, the Company has validated in this manner that 335 smelters or
refiners provided in supplier CMRTs are included on these lists. The facilities determined to be legitimate smelters or refiners based
on this comparison to the RMI-maintained list have also been compared to the RMI&rsquo;s RMAP list. Based on this comparison, the Company
is aware of 231 compliant smelters or refiners, 18 smelters or refiners that have begun the process and are deemed as active in the RMAP
but have not yet been validated as conflict free and 69 smelters or refiners that are not enrolled in the process to become compliant
to the RMAP. Confirmed smelter or refiner sourcing is not generally available through public information sources related to the smelter
or refiner. Despite the additional smelter information obtained from these suppliers, in most cases information has been provided on a
company or division level, rather than on a component level. Therefore, the Company cannot yet ascertain whether the smelters identified
by its suppliers are related to any parts or components provided to the Company by the suppliers.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Efforts to determine mine or location of origin</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">As noted above, the current efforts focus
on gathering smelter information via the CMRT reporting template and, as the program progresses, requiring full completion of all necessary
smelter identification information which will enable the validation and disclosure of the smelters as well as the tracing of the Conflict
Minerals to their location of origin. Seeking information about Conflict Minerals smelters and refiners in the Company&rsquo;s supply
chain represents the most reasonable effort the Company can make to determine the mines or locations of origin of the Conflict Minerals
in its supply chain.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B><U>6. Steps to improve future due diligence and to mitigate risk</U></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 1pt 0pt 0; text-align: justify">The Company intends to take the following
steps to improve its due diligence process to further mitigate any risk that the necessary Conflict Minerals in the Company&rsquo;s products
could benefit armed groups in the Covered Countries:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="padding-right: 13pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Continue to engage with suppliers and direct
them to training resources to attempt to increase the response rate and improve the content of the supplier survey responses.</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="padding-right: 6pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Suppliers will continue to be requested to inform
Harvard Bioscience of the correlation between these smelters and the products and parts they supply to Harvard Bioscience</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 8pt 0pt 5.4pt">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol">&middot;</FONT></TD><TD STYLE="padding-right: 8pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Continue to engage any suppliers found to be supplying
the Company with Conflict Minerals from sources that support conflict in any Covered Country to establish an alternative source of Conflict
Minerals that does not support such conflict.</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 4pt 0pt 5.4pt; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0.25in"></TD><TD STYLE="width: 0.25in"><FONT STYLE="font-family: Symbol; font-size: 10pt">&middot;</FONT></TD><TD STYLE="text-align: justify; padding-right: 4pt"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Continue
to evaluate upstream sources through a broader set of tools to evaluate risk that includes using a comprehensive smelter and refinery
library with detailed status and notes for each listing, scanning for credible media on each smelter and refinery to flag risk issues,
and comparing the list of smelters and refiners against government watch and denied parties lists.</FONT></TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

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