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Note 15 - Litigation Settlement (Details Textual) - USD ($) |  | 3 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Jun. 10, 2022 | Jun. 30, 2022 | Dec. 31, 2022 | Dec. 31, 2021 | Sep. 30, 2022 | Mar. 31, 2022
Litigation Settlement, Expense |  |  | $ (233,000) | $ 0 |  |
Series E Preferred Stock in Biostage [Member] |  |  |  |  |  |
Stock Issued During Period, Value, Issued for Settlement |  |  | 3,900,000 |  |  |
Equity Securities without Readily Determinable Fair Value, Amount | $ 3,900,000 |  |  |  |  |
Preferred Stock, Book Value, Inclusive of Accrued Dividends |  |  | $ 4,100,000 |  |  |
Convertible Preferred Stock [Member] | Biostage [Member] |  |  |  |  |  |
Preferred Stock, Dividend Rate, Percentage |  |  | 8.00% |  |  |
Preferred Stock, Par or Stated Value Per Share (in dollars per share) |  |  | $ 1,000 |  |  |
Preferred Stock, Mandatory Conversion, Minimum Qualified Offering Amount |  |  | $ 4,000,000 |  |  |
Case in Suffolk Superior Court [Member] |  |  |  |  |  |
Loss Contingency, Estimate of Possible Loss |  |  |  |  |  | $ 5,200,000
Legal Fees |  |  |  | $ 300,000 |  |
Litigation Settlement, Expense |  | $ (4,900,000) |  |  |  |
Case in Suffolk Superior Court [Member] | Convertible Preferred Stock [Member] |  |  |  |  |  |
Estimated Litigation Liability |  |  |  |  | $ 500,000 |
Stock Issued During Period, Shares, Issued For Settlement (in shares) | 4,000 |  |  |  |  |
Stock Issued During Period, Value, Issued for Settlement | $ 4,000,000.0 |  |  |  |  |

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