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Note 2 - Summary of Significant Accounting Policies (Details Textual) $ in Thousands		12 Months Ended
	Jun. 10, 2022 USD ($) shares	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Cash and Cash Equivalents, at Carrying Value, Total		$ 4,508	$ 7,821
Percentage of Cash and Cash Equivalents Held by Foreign Subsidiaries		56.00%
Number of Reporting Units		1
Goodwill, Impairment Loss		$ 0
Impairment of Long-Lived Assets Held-for-use		0
Series E Preferred Stock in Biostage [Member]
Stock Issued During Period, Value, Issued for Settlement		$ 3,900
Case in Suffolk Superior Court [Member] | Contingent Convertible Preferred Stock [Member]
Stock Issued During Period, Shares, Issued For Settlement (in shares) | shares	4,000
Stock Issued During Period, Value, Issued for Settlement	$ 4,000
Minimum [Member]
Customer Payments Term (Day)		0 days
Finite-Lived Intangible Asset, Useful Life (Year)		4 years
Minimum [Member] | Restricted Stock Units (RSUs) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)		1 year
Maximum [Member]
Customer Payments Term (Day)		60 days
Finite-Lived Intangible Asset, Useful Life (Year)		15 years
Maximum [Member] | Restricted Stock Units (RSUs) [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period (Year)		4 years

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