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STOCK-BASED COMPENSATION (Tables)
9 Months Ended
Sep. 30, 2012
Disclosure Of Compensation Related Costs, Share-Based Payments [Abstract]  
Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block]

The following table summarizes amounts charged to expense for stock-based compensation related to employee and director stock option grants and stock-based compensation recorded in connection with stock options granted to non-employee consultants:

 

Three Months Ended
September 30,
Nine Months Ended
September 30,
Cumulative
Development
Stage Period
from
November 7,
2002 through
September 30,
20122011201220112012
Employee and director stock option grants:
Research and development$78,627$66,402$234,816$121,393$723,374
General and administrative249,562213,326747,808349,7812,895,995
328,189279,728982,624471,1743,619,369
Non-employee consultant stock option grants:
Research and development3,89629,56485,26546,851121,422
General and administrative4,35188,77892,022137,631273,993
8,247118,342177,287184,482395,415
Total stock-based compensation$336,436$398,070$1,159,911$655,656$4,014,784
Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

The following table summarizes weighted-average values and assumptions used for options granted to employees, directors and consultants in the periods indicated:

 

    Three and Nine
Months Ended
September 30,
2012
    Nine Months
Ended
September 30,
2011
 
Volatility     115 %     110 %
Risk-free interest rate     0.925 %     1.84% – 3.17 %
Expected life (years)     6.0       5.5 – 6.25  
Dividend     0 %     0 %
Weighted-average exercise price   $ 1.00     $ 1.45  
Weighted-average grant-date fair value   $ 0.85     $ 1.22  
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

A summary of stock option activity under stock option plans is as follows:

 

    Number of
Shares
Issuable Upon
Exercise of
Outstanding
Options
    Weighted
Average
Exercise Price
    Weighted
Average
Remaining
Contracted
Term in
Years
    Aggregate
Intrinsic
Value
 
Outstanding at December 31, 2011     4,827,638     $ 1.82                  
Granted                              
Outstanding at March 31, 2012     4,827,638     $ 1.82                  
Granted                              
Outstanding at June 30, 2012     4,827,638     $ 1.82                  
Granted     24,000     $ 1.00                  
Forfeited     (175,884 )   $ 1.36                  
Outstanding at September 30, 2012     4,675,754                          
                                 
Vested, September 30, 2012     1,954,046     $ 2.92       8.69     $ 252,062  
Unvested, September 30, 2012     2,721,708     $ 1.06       8.87     $ 620,198  
Exercisable at September 30, 2012     1,954,046     $ 2.92       8.69     $ 252,062