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STOCKHOLDERS' EQUITY (Tables) | 12 Months Ended
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Dec. 31, 2014
Equity [Abstract] |
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] | The following table summarizes information with regard to outstanding warrants to purchase common stock as of December 31, 2014.
Offering |  |  | Number of Shares Issuable Upon Exercise of Outstanding Warrants |  | Exercise Price |  | Expiration Date |
August 2014 Public Offering (1) |  |  | 5,040,011 |  | $ | 4.68 |  | August 20, 2019 |
February 2013 Public Offering (1) |  |  | 550,000 |  | $ | 3.75 |  | February 20, 2018 |
February 2013 Public Offering – Placement Agents |  |  | 38,496 |  | $ | 12.50 |  | February 4, 2018 |
November 2012 Private Placement |  |  | 50,000 |  | $ | 25.00 |  | November 2, 2017 |
June 2012 Public Offering |  |  | 149,069 |  | $ | 25.00 |  | June 13, 2017 |
December 2011 Underwritten Offering |  |  | 462,411 |  | $ | 12.00 |  | December 6, 2016 |
April 2011 Private Placement |  |  | 302,922 |  | $ | 15.00 |  | March 31, 2016 |
Legacy warrants (1) |  |  | 1,365 |  | $ | 3.75 |  | July 27, 2015 |
Legacy warrants |  |  | 5,252 |  | $ | 321.30 |  | July 27, 2015 |
Legacy warrants |  |  | 4,570 |  | $ | 1,989-2,019.60 |  | December 31, 2015 |
Total |  |  | 6,604,096 |  |  |  |  |  |
| (1) | These warrants have a certain type of cash settlement feature or their exercise prices or the number of shares for which the warrant may be exercised are subject to adjustment for “down-rounds” and the warrants have been accounted for as derivative instruments as described in Note 3, with the exception of 96,988 warrants issued in August 2014.
Reserved For Future Issuance Upon Exercise Of Stock Options And Warrants Or Conversion Of Debt Text Block [Table Text Block] | The following shares were reserved for future issuance upon exercise of stock options and warrants:
|  | December 31, |
|  | 2014 |  | 2013 |
Warrants |  |  | 6,604,096 |  |  | 1,839,123 |
Stock options |  |  | 719,466 |  |  | 634,658 |
Total number of shares reserved for future issuance |  |  | 7,323,562 |  |  | 2,473,781 |

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- Definition Tabular disclosure of reserved for future issuance upon exercise of stock options and warrants or conversion of debt. + References No definition available. + Details
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- Definition Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 235 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.4-08.(i)) -URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e23780-122690 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 08 -Paragraph i -Article 4 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6406099&loc=d3e25284-112666 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 50 -Section S99 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6784392&loc=d3e188667-122775 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 28 -Article 5 + Details
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