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STOCK-BASED COMPENSATION (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] |  |
Total stock-based compensation | $ 467,541 | $ 866,791
Employee and director stock option grants [Member] | Research and development [Member] |  |
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] |  |
Total stock-based compensation | 72,579 | 62,932
Employee and director stock option grants [Member] | General and administrative [Member] |  |
Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Line Items] |  |
Total stock-based compensation | $ 394,962 | $ 803,859

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