    <SEC-DOCUMENT>0001047469-15-007251-index.html : 20150911
    <SEC-HEADER>0001047469-15-007251.hdr.sgml : 20150911
    <ACCEPTANCE-DATETIME>20150911060219
    ACCESSION NUMBER:		0001047469-15-007251
    CONFORMED SUBMISSION TYPE:	S-1/A
    PUBLIC DOCUMENT COUNT:		60
    FILED AS OF DATE:		20150911
    DATE AS OF CHANGE:		20150911

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Mirna Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0001527599
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				261824804
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		S-1/A
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-206544
    		FILM NUMBER:		151102260

    	BUSINESS ADDRESS:
    		STREET 1:		2150 WOODWARD ST., SUITE 100
    		CITY:			AUSTIN
    		STATE:			TX
    		ZIP:			78744
    		BUSINESS PHONE:		512-681-5252

    	MAIL ADDRESS:
    		STREET 1:		2150 WOODWARD ST., SUITE 100
    		CITY:			AUSTIN
    		STATE:			TX
    		ZIP:			78744
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>S-1/A
    <SEQUENCE>1
    <FILENAME>a2225898zs-1a.htm
    <DESCRIPTION>S-1/A
    <TEXT>
    Document 1 - file: a2225898zs-1a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.3
    <SEQUENCE>2
    <FILENAME>a2225898zex-3_3.htm
    <DESCRIPTION>EX-3.3
    <TEXT>
    Document 2 - file: a2225898zex-3_3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.5
    <SEQUENCE>3
    <FILENAME>a2225898zex-3_5.htm
    <DESCRIPTION>EX-3.5
    <TEXT>
    Document 3 - file: a2225898zex-3_5.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.3
    <SEQUENCE>4
    <FILENAME>a2225898zex-4_3.htm
    <DESCRIPTION>EX-4.3
    <TEXT>
    Document 4 - file: a2225898zex-4_3.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-4.4
    <SEQUENCE>5
    <FILENAME>a2225898zex-4_4.htm
    <DESCRIPTION>EX-4.4
    <TEXT>
    Document 5 - file: a2225898zex-4_4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(A)
    <SEQUENCE>6
    <FILENAME>a2225898zex-10_3a.htm
    <DESCRIPTION>EX-10.3(A)
    <TEXT>
    Document 6 - file: a2225898zex-10_3a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(D)
    <SEQUENCE>7
    <FILENAME>a2225898zex-10_3d.htm
    <DESCRIPTION>EX-10.3(D)
    <TEXT>
    Document 7 - file: a2225898zex-10_3d.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(E)
    <SEQUENCE>8
    <FILENAME>a2225898zex-10_3e.htm
    <DESCRIPTION>EX-10.3(E)
    <TEXT>
    Document 8 - file: a2225898zex-10_3e.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(F)
    <SEQUENCE>9
    <FILENAME>a2225898zex-10_3f.htm
    <DESCRIPTION>EX-10.3(F)
    <TEXT>
    Document 9 - file: a2225898zex-10_3f.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.3(G)
    <SEQUENCE>10
    <FILENAME>a2225898zex-10_3g.htm
    <DESCRIPTION>EX-10.3(G)
    <TEXT>
    Document 10 - file: a2225898zex-10_3g.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.4
    <SEQUENCE>11
    <FILENAME>a2225898zex-10_4.htm
    <DESCRIPTION>EX-10.4
    <TEXT>
    Document 11 - file: a2225898zex-10_4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.5
    <SEQUENCE>12
    <FILENAME>a2225898zex-10_5.htm
    <DESCRIPTION>EX-10.5
    <TEXT>
    Document 12 - file: a2225898zex-10_5.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.9(A)
    <SEQUENCE>13
    <FILENAME>a2225898zex-10_9a.htm
    <DESCRIPTION>EX-10.9(A)
    <TEXT>
    Document 13 - file: a2225898zex-10_9a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.9(B)
    <SEQUENCE>14
    <FILENAME>a2225898zex-10_9b.htm
    <DESCRIPTION>EX-10.9(B)
    <TEXT>
    Document 14 - file: a2225898zex-10_9b.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.9(C)
    <SEQUENCE>15
    <FILENAME>a2225898zex-10_9c.htm
    <DESCRIPTION>EX-10.9(C)
    <TEXT>
    Document 15 - file: a2225898zex-10_9c.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.10
    <SEQUENCE>16
    <FILENAME>a2225898zex-10_10.htm
    <DESCRIPTION>EX-10.10
    <TEXT>
    Document 16 - file: a2225898zex-10_10.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.11
    <SEQUENCE>17
    <FILENAME>a2225898zex-10_11.htm
    <DESCRIPTION>EX-10.11
    <TEXT>
    Document 17 - file: a2225898zex-10_11.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.12
    <SEQUENCE>18
    <FILENAME>a2225898zex-10_12.htm
    <DESCRIPTION>EX-10.12
    <TEXT>
    Document 18 - file: a2225898zex-10_12.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.13
    <SEQUENCE>19
    <FILENAME>a2225898zex-10_13.htm
    <DESCRIPTION>EX-10.13
    <TEXT>
    Document 19 - file: a2225898zex-10_13.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.15
    <SEQUENCE>20
    <FILENAME>a2225898zex-10_15.htm
    <DESCRIPTION>EX-10.15
    <TEXT>
    Document 20 - file: a2225898zex-10_15.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.16(A)
    <SEQUENCE>21
    <FILENAME>a2225898zex-10_16a.htm
    <DESCRIPTION>EX-10.16(A)
    <TEXT>
    Document 21 - file: a2225898zex-10_16a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.16(B)
    <SEQUENCE>22
    <FILENAME>a2225898zex-10_16b.htm
    <DESCRIPTION>EX-10.16(B)
    <TEXT>
    Document 22 - file: a2225898zex-10_16b.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.17(A)
    <SEQUENCE>23
    <FILENAME>a2225898zex-10_17a.htm
    <DESCRIPTION>EX-10.17(A)
    <TEXT>
    Document 23 - file: a2225898zex-10_17a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.17(B)
    <SEQUENCE>24
    <FILENAME>a2225898zex-10_17b.htm
    <DESCRIPTION>EX-10.17(B)
    <TEXT>
    Document 24 - file: a2225898zex-10_17b.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.18
    <SEQUENCE>25
    <FILENAME>a2225898zex-10_18.htm
    <DESCRIPTION>EX-10.18
    <TEXT>
    Document 25 - file: a2225898zex-10_18.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-10.19
    <SEQUENCE>26
    <FILENAME>a2225898zex-10_19.htm
    <DESCRIPTION>EX-10.19
    <TEXT>
    Document 26 - file: a2225898zex-10_19.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-23.1
    <SEQUENCE>27
    <FILENAME>a2225898zex-23_1.htm
    <DESCRIPTION>EX-23.1
    <TEXT>
    Document 27 - file: a2225898zex-23_1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>g559585.jpg
    <DESCRIPTION>G559585.JPG
    <TEXT>
    Document 28 - file: g559585.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>g416012.jpg
    <DESCRIPTION>G416012.JPG
    <TEXT>
    Document 29 - file: g416012.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>30
    <FILENAME>g243128.jpg
    <DESCRIPTION>G243128.JPG
    <TEXT>
    Document 30 - file: g243128.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>g121996.jpg
    <DESCRIPTION>G121996.JPG
    <TEXT>
    Document 31 - file: g121996.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>32
    <FILENAME>g393531.jpg
    <DESCRIPTION>G393531.JPG
    <TEXT>
    Document 32 - file: g393531.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>33
    <FILENAME>g407866.jpg
    <DESCRIPTION>G407866.JPG
    <TEXT>
    Document 33 - file: g407866.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>34
    <FILENAME>g766180.jpg
    <DESCRIPTION>G766180.JPG
    <TEXT>
    Document 34 - file: g766180.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>35
    <FILENAME>g877907.jpg
    <DESCRIPTION>G877907.JPG
    <TEXT>
    Document 35 - file: g877907.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>36
    <FILENAME>g362748.jpg
    <DESCRIPTION>G362748.JPG
    <TEXT>
    Document 36 - file: g362748.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>37
    <FILENAME>g573882.jpg
    <DESCRIPTION>G573882.JPG
    <TEXT>
    Document 37 - file: g573882.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>38
    <FILENAME>g435121.jpg
    <DESCRIPTION>G435121.JPG
    <TEXT>
    Document 38 - file: g435121.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>39
    <FILENAME>g784076.jpg
    <DESCRIPTION>G784076.JPG
    <TEXT>
    Document 39 - file: g784076.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>40
    <FILENAME>g369388.jpg
    <DESCRIPTION>G369388.JPG
    <TEXT>
    Document 40 - file: g369388.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>41
    <FILENAME>g741128.jpg
    <DESCRIPTION>G741128.JPG
    <TEXT>
    Document 41 - file: g741128.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>42
    <FILENAME>g69549.jpg
    <DESCRIPTION>G69549.JPG
    <TEXT>
    Document 42 - file: g69549.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>43
    <FILENAME>g715702.jpg
    <DESCRIPTION>G715702.JPG
    <TEXT>
    Document 43 - file: g715702.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>44
    <FILENAME>g522893.jpg
    <DESCRIPTION>G522893.JPG
    <TEXT>
    Document 44 - file: g522893.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>45
    <FILENAME>g101140.jpg
    <DESCRIPTION>G101140.JPG
    <TEXT>
    Document 45 - file: g101140.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>46
    <FILENAME>g9237.jpg
    <DESCRIPTION>G9237.JPG
    <TEXT>
    Document 46 - file: g9237.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>47
    <FILENAME>g361638.jpg
    <DESCRIPTION>G361638.JPG
    <TEXT>
    Document 47 - file: g361638.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>48
    <FILENAME>g146442mmi001.jpg
    <DESCRIPTION>G146442MMI001.JPG
    <TEXT>
    Document 48 - file: g146442mmi001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>49
    <FILENAME>g146442mg01i001.jpg
    <DESCRIPTION>G146442MG01I001.JPG
    <TEXT>
    Document 49 - file: g146442mg01i001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>50
    <FILENAME>g146442mg01i002.jpg
    <DESCRIPTION>G146442MG01I002.JPG
    <TEXT>
    Document 50 - file: g146442mg01i002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>51
    <FILENAME>g146442mg07i001.jpg
    <DESCRIPTION>G146442MG07I001.JPG
    <TEXT>
    Document 51 - file: g146442mg07i001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>52
    <FILENAME>g146442mg07i002.jpg
    <DESCRIPTION>G146442MG07I002.JPG
    <TEXT>
    Document 52 - file: g146442mg07i002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>53
    <FILENAME>g146442mg07i003.jpg
    <DESCRIPTION>G146442MG07I003.JPG
    <TEXT>
    Document 53 - file: g146442mg07i003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>54
    <FILENAME>g146442mg09i001.jpg
    <DESCRIPTION>G146442MG09I001.JPG
    <TEXT>
    Document 54 - file: g146442mg09i001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>55
    <FILENAME>g146442mg09i002.jpg
    <DESCRIPTION>G146442MG09I002.JPG
    <TEXT>
    Document 55 - file: g146442mg09i002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>56
    <FILENAME>g146442mg11i001.jpg
    <DESCRIPTION>G146442MG11I001.JPG
    <TEXT>
    Document 56 - file: g146442mg11i001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>57
    <FILENAME>g146442mg13i001.jpg
    <DESCRIPTION>G146442MG13I001.JPG
    <TEXT>
    Document 57 - file: g146442mg13i001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>58
    <FILENAME>g146442mg13i002.jpg
    <DESCRIPTION>G146442MG13I002.JPG
    <TEXT>
    Document 58 - file: g146442mg13i002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>59
    <FILENAME>g146442mg13i003.jpg
    <DESCRIPTION>G146442MG13I003.JPG
    <TEXT>
    Document 59 - file: g146442mg13i003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>60
    <FILENAME>g146442mg13i004.jpg
    <DESCRIPTION>G146442MG13I004.JPG
    <TEXT>
    Document 60 - file: g146442mg13i004.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>