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Stock Option Plans (Tables)
9 Months Ended
Sep. 30, 2016
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Stock Option Activity
The Company’s stock option activity for the nine months ended September 30, 2016 was as follows:
 
 
 
 
Weighted‑
 
 
 
 
 
 
Average
 
Weighted‑Average
 
 
Number
 
Exercise
 
Contractual
 
 
of Shares
 
Price
 
Life (years)
Outstanding at December 31, 2015
 
1,529,459

 
6.29

 
9.00
Granted
 
928,250

 
4.41

 
 
Exercised
 
(5,313
)
 
1.65

 
 
Forfeited/canceled
 
(350,432
)
 
6.85

 
 
Outstanding at September 30, 2016
 
2,101,964

 
$
5.37

 
8.65
Options exercisable at September 30, 2016
 
646,142

 
$
5.33

 
7.40
Schedule of Stock Compensation Expense
Total stock-based compensation expense for the three and nine months ended September 30, 2016 was recognized as follows in the statements of comprehensive loss (in thousands):
 
 
 
Three Months Ended
September 30,
 
Nine Months Ended
September 30,
 
 
2016
 
2015
 
2016
 
2015
Research and development expense
 
$
155

 
$
57

 
$
261

 
$
137

General and administrative expense
 
358

 
153

 
941

 
424

Total stock based compensation
 
$
513

 
$
210

 
$
1,202

 
$
561