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Stock Option Plans (Tables)
 6 Months Ended
Jun. 30, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Schedule of Stock Option Activity
The Company’s stock option activity for the six months ended June 30, 2017 was as follows:
 
 
 
 
Weighted‑
 
 
 
 
 
 
Average
 
Weighted‑Average
 
 
Number
 
Exercise
 
Contractual
 
 
of Shares
 
Price
 
Life (years)
Outstanding at December 31, 2016
 
1,905,214

 
$
5.39

 
7.49
Granted
 
—

 
—

 
 
Exercised
 
(15,300
)
 
1.65

 
 
Forfeited/canceled
 
(302,040
)
 
5.46

 
 
Outstanding at June 30, 2017
 
1,587,874

 
$
5.41

 
7.80
Options exercisable at June 30, 2017
 
1,134,680

 
$
5.24

 
7.58
Schedule of Stock Compensation Expense
Total stock-based compensation expense for the three and six months ended June 30, 2017 was recognized as follows in the statements of comprehensive loss (in thousands):
 
 
 
Three Months Ended
June 30,
 
Six Months Ended
June 30,
 
 
2017
 
2016
 
2017
 
2016
Research and development expense
 
$
30

 
$
(56
)
 
$
71

 
$
115

General and administrative expense
 
299

 
298

 
622

 
574

Total stock based compensation
 
$
329

 
$
242

 
$
693

 
$
689