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Restructuring Charges - Narrative (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
May 31, 2017
USD ($)
Feb. 28, 2017
USD ($)
Jun. 30, 2017
USD ($)
employee
Dec. 31, 2016
USD ($)
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
employee
Jun. 30, 2016
USD ($)
Jun. 30, 2017
USD ($)
employee
Dec. 31, 2016
USD ($)
Sep. 28, 2016
employee
Sep. 27, 2016
employee
Restructuring Cost and Reserve [Line Items]                      
Number of employees | employee     4     4   4   12 36
Restructuring expense       $ 4,400   $ 2,723   $ 7,200      
Non-cash impairment charges       1,400         $ 1,400    
Employee severance and related costs     $ 43   $ 0 248 $ 0        
Contract termination costs     122   0 2,475 0   1,500    
Total restructuring charges     165   $ 0 2,723 0        
Accrued restructuring     111 2,662   111   111 2,662    
Consideration paid for settlement of lease $ 3,800                    
Cash consideration for sale of lab equipment           325 $ 0        
Lab Equipment                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges                 555    
Cash consideration for sale of lab equipment   $ 325                  
Construction in Progress                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges                 591    
Furniture, Computers, Equipment, and Leasehold Improvements                      
Restructuring Cost and Reserve [Line Items]                      
Non-cash impairment charges                 256    
Contract Termination Costs                      
Restructuring Cost and Reserve [Line Items]                      
Restructuring expense           2,475          
Accrued restructuring     $ 0 $ 1,565   $ 0   $ 0 $ 1,565