<SEC-DOCUMENT>0001193125-18-256311-index.html : 20180823
<SEC-HEADER>0001193125-18-256311.hdr.sgml : 20180823
<ACCEPTANCE-DATETIME>20180823161750
ACCESSION NUMBER:		0001193125-18-256311
CONFORMED SUBMISSION TYPE:	S-3/A
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20180823
DATE AS OF CHANGE:		20180823

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SYNLOGIC, INC.
		CENTRAL INDEX KEY:			0001527599
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				261824804
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-226730
		FILM NUMBER:		181034946

	BUSINESS ADDRESS:	
		STREET 1:		301 BINNEY STREET
		STREET 2:		SUITE 402
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-401-9975

	MAIL ADDRESS:	
		STREET 1:		301 BINNEY STREET
		STREET 2:		SUITE 402
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Mirna Therapeutics, Inc.
		DATE OF NAME CHANGE:	20110809
</SEC-HEADER>
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<SEQUENCE>1
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<TEXT>
Document 1 - file: d605794ds3a.htm

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<DESCRIPTION>EX-5.1
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Document 2 - file: d605794dex51.htm

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<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g605794g15x76.gif

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<SEQUENCE>4
<FILENAME>g605794g46i08.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g605794g46i08.gif

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Document 5 - file: g605794g61z60.gif

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