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Leases - Additional Information (Detail) | 1 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
Jul. 31, 2017 USD ($) ft² | Jul. 31, 2015 USD ($) | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Jun. 30, 2017 USD ($) Agreement | Oct. 31, 2016 USD ($)
Lessee Lease Description [Line Items] |  |  |  |  |  |
Operating Lease Annual Rent |  |  | $ 2,500,000 |  |  |
Rent credit due to accelerated amortization of deferred rent |  |  |  | $ 200,000 |  |
Remaining amortization period of deferred rent and remaining useful life leasehold improvements | 63 months |  |  |  |  |
Revised amortization period of deferred rent and revised useful life leasehold improvements | 7 months | 7 months |  |  |  |
Laboratory and office space to be leased | ft² | 41,346 |  |  |  |  |
Operating lease annual rent | $ 3,100,000 | $ 900,000 |  |  |  |
Term of lease | 10 years | 63 months |  |  |  |
Tenant improvement investment | $ 1,600,000 |  |  |  |  |
Capitalized landlord tenant improvement funded |  |  | $ 5,000,000 |  |  |
Letter of credit | 1,000,000 |  |  |  |  |
Lease commencement date |  | 2016-02 |  |  |  |
Lease expiration date |  | 2021-04 | 2017-07 |  |  |
Renewal term of lease |  | 1 year |  |  |  |
Agreement termination term |  | 30 days |  |  |  |
Penalty on contract termination |  | $ 0 |  |  |  |
Yearly increases in base rent |  | 3.00% |  |  |  |
Rent abatement term |  | 3 months |  |  |  |
Number of non cancellable lease agreements | Agreement |  |  |  |  | 2 |
Non cancellable lease agreements description |  |  | the present value of the lease exceeds 90% of the fair market value. |  |  |
Agreement termination |  |  | 2018-11 |  |  |
Non-cancellable Lease Agreement Three |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |
Term of non-cancellable lease |  |  |  |  | 36 months |
Non-cancellable lease |  |  |  |  | $ 200,000 |
Interest rate on outstanding capital lease obligation |  |  | 1.10% |  |  |
Non-cancellable Lease Agreement Four |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |
Term of non-cancellable lease |  |  |  |  | 36 months |
Non-cancellable lease |  |  |  |  | $ 700,000 |
Interest rate on outstanding capital lease obligation |  |  | 7.30% |  |  |
Non Cancellable Lease Agreement Two |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |
Term of non-cancellable lease |  |  |  |  |  | 24 months
Non-cancellable lease |  |  |  |  |  | $ 400,000
Interest rate on outstanding capital lease obligation |  |  |  | 9.60% |  |
Maximum |  |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |  |
Tenant improvement investment | $ 6,600,000 |  |  |  |  |

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