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Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Dec. 31, 2018
Dec. 31, 2017
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 17,828 $ 12,898
Less accumulated depreciation (2,987) (3,115)
Property and equipment, net 14,841 9,783
Laboratory Equipment    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 7,111 2,999
Computer and Office Equipment    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 781 354
Furniture and Fixtures    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 413 220
Leasehold Improvements    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 9,484 2,308
Construction in Progress    
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 39 $ 7,017