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Equity-based Compensation and Equity Incentive Plans (Tables) | 3 Months Ended
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Mar. 31, 2019
Schedule of Restricted Common Stock Activity | The following table shows restricted stock activity during the three months ended March 31, 2019:
|  | Restricted stock awards |
|  |  |  |  |  | Grant date |
|  | Number of |  |  | fair value |
|  | shares |  |  | (per share) |
Unvested at December 31, 2018 |  |  | 118,679 |  |  | $ | 13.54 |
Granted |  |  | — |  |  |  | — |
Vested |  |  | (18,124 | ) |  |  | 13.53 |
Forfeited |  |  | (12,836 | ) |  |  | 13.53 |
Unvested at March 31, 2019 |  |  | 87,719 |  |  | $ | 13.55 |
Schedule of Equity-based Compensation Expenses | The following table summarizes equity‑based compensation expense within the Company’s consolidated statements of operations and comprehensive loss for the three months ended March 31, 2019 and 2018 (in thousands):
|  | Three Months Ended March 31, |
|  | 2019 |  |  | 2018 |
Research and development |  | $ | 284 |  |  | $ | 377 |
General and administrative |  |  | 670 |  |  |  | 542 |
|  | $ | 954 |  |  | $ | 919 |
Schedule of Equity-based Compensation Expenses by Award Type | The following table summarizes equity‑based compensation expense by type of award for the three months ended March 31, 2019 and 2018 (in thousands):
|  | Three Months Ended March 31, |
|  | 2019 |  |  | 2018 |
Stock options |  | $ | 926 |  |  | $ | 773 |
Restricted stock awards |  |  | 28 |  |  |  | 146 |
|  | $ | 954 |  |  | $ | 919 |
2015 and 2017 Plan |
Schedule of Stock Option Activity | The following table summarizes stock option activity during the three months ended March 31, 2019 under the 2015 Plan and the 2017 Plan.
|  | Stock options outstanding |
|  |  |  |  |  |  |  |  |  | Weighted |  |  |  |  |
|  |  |  |  |  | Weighted |  |  | average |  |  | Aggregate |
|  |  |  |  |  | average |  |  | remaining |  |  | Intrinsic |
|  | Number of |  |  | exercise |  |  | contractual |  |  | value (a) |
|  | options |  |  | price |  |  | term (in years) |  |  | (in thousands) |
Outstanding at December 31, 2018 |  |  | 1,739,884 |  |  | $ | 11.92 |  |  |  | 9.0 |  |  | $ | — |
Granted |  |  | 1,163,980 |  |  |  | 8.54 |  |  |  |  |  |  |  |  |
Exercised |  |  | — |  |  |  | — |  |  |  |  |  |  |  |  |
Forfeited |  |  | (156,821 | ) |  |  | 13.84 |  |  |  |  |  |  |  |  |
Outstanding at March 31, 2019 |  |  | 2,747,043 |  |  |  | 10.38 |  |  |  | 9.2 |  |  | $ | 2,030 |
Vested or expected to vest at March 31, 2019 |  |  | 2,747,043 |  |  |  | 10.38 |  |  |  | 9.2 |  |  |  | 2,030 |
Exercisable at March 31, 2019 |  |  | 558,274 |  |  |  | 13.10 |  |  |  | 8.5 |  |  | $ | — |
| (a) | The aggregate intrinsic value is calculated as the difference between the exercise price of the options and the fair market value of the underlying common stock for the options that were in the money at March 31, 2019 and December 31, 2018.

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- Definition Tabular disclosure of components of a stock option or other award plan under which equity-based compensation is awarded to employees, typically comprised of the amount of unearned compensation (deferred compensation cost), compensation expense, and changes in the quantity and fair value of the shares (or other type of equity) granted, exercised, forfeited, and issued and outstanding pertaining to that plan. Disclosure may also include nature and general terms of such arrangements that existed during the period and potential effects of those arrangements on shareholders, effect of compensation cost arising from equity-based payment arrangements on the income statement, method of estimating the fair value of the goods or services received, or the fair value of the equity instruments granted, during the period, cash flow effects resulting from equity-based payment arrangements and, for registrants that accelerate vesting of out of the money share options, reasons for the decision to accelerate. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the changes in outstanding nonvested restricted stock shares. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901 + Details
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