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Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 18,018	$ 17,828
Less accumulated depreciation	(3,670)	(2,987)
Property and equipment, net	14,348	14,841
Laboratory Equipment
Property Plant And Equipment [Line Items]
Property and equipment, gross	7,287	7,111
Computer and Office Equipment
Property Plant And Equipment [Line Items]
Property and equipment, gross	829	781
Furniture and Fixtures
Property Plant And Equipment [Line Items]
Property and equipment, gross	413	413
Leasehold Improvements
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,484	9,484
Construction in Progress
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 5	$ 39

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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