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Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Income Statement [Abstract]
Revenue	$ 305	$ 1,801	$ 993	$ 2,409
Operating expenses:
Research and development	10,564	9,934	30,651	29,167
General and administrative	3,879	3,401	11,272	11,764
Total operating expenses	14,443	13,335	41,923	40,931
Loss from operations	(14,138)	(11,534)	(40,930)	(38,522)
Other income (expense):
Interest and investment income	857	797	2,373	2,059
Interest expense	(5)	(10)	(17)	(36)
Other expense	1	(1)	(1)	(5)
Other income (expense), net	853	786	2,355	2,018
Net loss	$ (13,285)	$ (10,748)	$ (38,575)	$ (36,504)
Net loss per share attributable to common shareholders - basic and diluted	$ (0.39)	$ (0.43)	$ (1.33)	$ (1.56)
Weighted-average common shares used in computing net loss per share attributable to common shareholders - basic and diluted	34,213,096	25,208,117	28,956,280	23,415,242
Comprehensive loss:
Net loss	$ (13,285)	$ (10,748)	$ (38,575)	$ (36,504)
Net unrealized gains (losses) on marketable securities	46	28	179	(38)
Comprehensive loss	$ (13,239)	$ (10,720)	$ (38,396)	$ (36,542)

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