    <SEC-DOCUMENT>0001157523-19-001827-index.html : 20190813
    <SEC-HEADER>0001157523-19-001827.hdr.sgml : 20190813
    <ACCEPTANCE-DATETIME>20190813074522
    ACCESSION NUMBER:		0001157523-19-001827
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		31
    CONFORMED PERIOD OF REPORT:	20190813
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20190813
    DATE AS OF CHANGE:		20190813

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			SYNLOGIC, INC.
    		CENTRAL INDEX KEY:			0001527599
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				261824804
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37566
    		FILM NUMBER:		191018252

    	BUSINESS ADDRESS:
    		STREET 1:		301 BINNEY STREET
    		STREET 2:		SUITE 402
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142
    		BUSINESS PHONE:		617-401-9975

    	MAIL ADDRESS:
    		STREET 1:		301 BINNEY STREET
    		STREET 2:		SUITE 402
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Mirna Therapeutics, Inc.
    		DATE OF NAME CHANGE:	20110809
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>a52077954.htm
    <DESCRIPTION>SYNLOGIC, INC. 8-K
    <TEXT>
    Document 1 - file: a52077954.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>a52077954ex99_1.htm
    <DESCRIPTION>EXHIBIT 99.1
    <TEXT>
    Document 2 - file: a52077954ex99_1.htm

    </DOCUMENT>
    <DOCUMENT>
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    <SEQUENCE>3
    <FILENAME>a52077954ex99_1slide1.jpg
    <TEXT>
    Document 3 - file: a52077954ex99_1slide1.jpg

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    <SEQUENCE>4
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    <TEXT>
    Document 4 - file: a52077954ex99_1slide2.jpg

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    <SEQUENCE>5
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    Document 5 - file: a52077954ex99_1slide3.jpg

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    <SEQUENCE>6
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    <TEXT>
    Document 6 - file: a52077954ex99_1slide4.jpg

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    <SEQUENCE>7
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    <TEXT>
    Document 7 - file: a52077954ex99_1slide5.jpg

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    <SEQUENCE>8
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    Document 8 - file: a52077954ex99_1slide6.jpg

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    <SEQUENCE>9
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    <TEXT>
    Document 9 - file: a52077954ex99_1slide7.jpg

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    <SEQUENCE>10
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    <TEXT>
    Document 10 - file: a52077954ex99_1slide8.jpg

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    <SEQUENCE>11
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    <TEXT>
    Document 11 - file: a52077954ex99_1slide9.jpg

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    <SEQUENCE>12
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    <TEXT>
    Document 12 - file: a52077954ex99_1slide10.jpg

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    <SEQUENCE>13
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    <TEXT>
    Document 13 - file: a52077954ex99_1slide11.jpg

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    <SEQUENCE>14
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    <TEXT>
    Document 14 - file: a52077954ex99_1slide12.jpg

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    <SEQUENCE>15
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    Document 15 - file: a52077954ex99_1slide13.jpg

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    Document 16 - file: a52077954ex99_1slide14.jpg

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    <SEQUENCE>17
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    <TEXT>
    Document 17 - file: a52077954ex99_1slide15.jpg

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    <SEQUENCE>18
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    <TEXT>
    Document 18 - file: a52077954ex99_1slide16.jpg

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    <SEQUENCE>19
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    <TEXT>
    Document 19 - file: a52077954ex99_1slide17.jpg

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    <SEQUENCE>20
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    Document 20 - file: a52077954ex99_1slide18.jpg

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    <SEQUENCE>21
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    Document 21 - file: a52077954ex99_1slide19.jpg

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    <SEQUENCE>22
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    Document 22 - file: a52077954ex99_1slide20.jpg

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    <SEQUENCE>23
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    Document 23 - file: a52077954ex99_1slide21.jpg

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    <SEQUENCE>24
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    <TEXT>
    Document 24 - file: a52077954ex99_1slide22.jpg

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    <SEQUENCE>25
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    Document 25 - file: a52077954ex99_1slide23.jpg

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    <SEQUENCE>26
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    <TEXT>
    Document 26 - file: a52077954ex99_1slide24.jpg

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    <SEQUENCE>27
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    <TEXT>
    Document 27 - file: a52077954ex99_1slide25.jpg

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    <SEQUENCE>28
    <FILENAME>a52077954ex99_1slide26.jpg
    <TEXT>
    Document 28 - file: a52077954ex99_1slide26.jpg

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    <SEQUENCE>29
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    Document 29 - file: a52077954ex99_1slide27.jpg

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    <SEQUENCE>30
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    <TEXT>
    Document 30 - file: a52077954ex99_1slide28.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>31
    <FILENAME>a52077954ex99_1slide29.jpg
    <TEXT>
    Document 31 - file: a52077954ex99_1slide29.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>