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Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Total | Common Stock $0.001 Par Value | Additional Paid-in Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2017 | $ 85,038 | $ 16 | $ 156,685 | $ (9) | $ (71,654)
Balance (in Shares) at Dec. 31, 2017 |  | 16,272,617 |  |  |
Effect of adoption of ASU | ASU 2014-09 (ASC 606) | 324 |  |  |  | 324
Sale of common shares, net of issuance costs | 82,666 | $ 9 | 82,657 |  |
Sale of common shares, net of issuance costs, shares |  | 9,179,500 |  |  |
Exercise of options | 244 |  | 244 |  |
Exercise of options, shares |  | 19,830 |  |  |
Cancellation of restricted stock |  | (70,468) |  |  |
Equity-based compensation expense | 4,317 |  | 4,317 |  |
Unrealized gain (loss) on securities | (56) |  |  | (56) |
Net loss | (48,435) |  |  |  | (48,435)
Balance at Dec. 31, 2018 | 124,098 | $ 25 | 243,903 | (65) | (119,765)
Balance (in Shares) at Dec. 31, 2018 |  | 25,401,479 |  |  |
Sale of common shares, net of issuance costs | 56,997 | $ 7 | 56,990 |  |
Sale of common shares, net of issuance costs, shares |  | 6,340,771 |  |  |
Proceeds from issuance of pre-funded common stock warrants, net of issuance costs | 22,874 |  | 22,874 |  |
Issuance of restricted stock |  | $ 1 | (1) |  |
Issuance of restricted stock, shares |  | 585,600 |  |  |
Cancellation of restricted stock |  | (61,036) |  |  |
Equity-based compensation expense | 4,134 |  | 4,134 |  |
Unrealized gain (loss) on securities | 175 |  |  | 175 |
Net loss | (51,373) |  |  |  | (51,373)
Balance at Dec. 31, 2019 | $ 156,905 | $ 33 | $ 327,900 | $ 110 | $ (171,138)
Balance (in Shares) at Dec. 31, 2019 |  | 32,266,814 |  |  |

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