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v3.20.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2019 | Dec. 31, 2018
Cash flows from operating activities: |  |
Net loss | $ (51,373) | $ (48,435)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 2,702 | 2,421
Loss on disposal of property and equipment |  | 8
Equity-based compensation expense | 4,134 | 4,317
Accretion/amortization of investment securities | (1,282) | (1,401)
Reduction in carrying amount of operating lease right of use asset | 1,370 |
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (12,263) | (45)
Prepaid research and development, net of current portion | (16,381) |
Other assets |  | 168
Accounts payable and accrued expenses | (935) | (257)
Deferred revenue | 276 | (520)
Deferred rent |  | 1,274
Operating lease liabilities | (1,716) |
Net cash, cash equivalents and restricted cash used in operating activities | (75,468) | (42,470)
Cash flows from investing activities: |  |
Purchases of marketable securities | (145,418) | (172,887)
Proceeds from maturity of marketable securities | 157,465 | 91,340
Purchases of property and equipment | (1,251) | (5,654)
Net cash, cash equivalents and restricted cash provided by (used in) investing activities | 10,796 | (87,201)
Cash flows from financing activities: |  |
Payments on finance lease obligations | (266) | (427)
Proceeds from exercise of stock options |  | 244
Proceeds from sale of common stock, net of issuance costs | 56,996 | 82,666
Proceeds from sale of pre-funded warrants, net of issuance costs | 22,874 |
Net cash, cash equivalents and restricted cash provided by financing activities | 79,604 | 82,483
Net increase (decrease) in cash, cash equivalents and restricted cash | 14,932 | (47,188)
Cash, cash equivalents and restricted cash at beginning of period | 12,349 | 59,537
Cash, cash equivalents and restricted cash at end of period | 27,281 | 12,349
Supplemental disclosure of non-cash investing and financing activities: |  |
Landlord funded allowance for tenant improvements |  | 1,654
Property and equipment purchases included in accounts payable and accrued expenses | (369) | 169
Assets acquired under operating lease obligation | 2,714 |
Cash paid for interest | $ 21 | 43
Purchase under capital lease |  | $ 12

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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=118932676&loc=d3e3602-108585 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration