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Collaboration Agreements - Additional Information (Detail) $ in Thousands		1 Months Ended					3 Months Ended								12 Months Ended
	Sep. 27, 2018 USD ($) Milestone	Jun. 30, 2019 USD ($) shares	Apr. 30, 2018 shares	Jan. 31, 2018 shares	May 31, 2017 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2019 USD ($)	Sep. 30, 2019 USD ($)	Jun. 30, 2019 USD ($) shares	Mar. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Sep. 30, 2018 USD ($)	Jun. 30, 2018 USD ($)	Mar. 31, 2018 USD ($)	Dec. 31, 2019 USD ($) shares	Dec. 31, 2018 USD ($) shares	Feb. 28, 2019 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Recognition of revenue							$ 1,231	$ 305	$ 350	$ 338	$ 111	$ 1,801	$ 254	$ 354	$ 2,224	$ 2,520
Current deferred revenue							544				$ 268				$ 544	$ 268
Common Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of shares sold | shares			3,280,000	5,899,500											6,340,771	9,179,500
Ginkgo Collaboration
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Prepayment to related party for collaboration agreement		$ 30,000
Related party transaction collaboration agreement, initial term		5 years
Ginkgo Collaboration | Pre-Funded Warrants
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Warrants to purchase shares of common stock | shares		2,548,117							2,548,117
Ginkgo Collaboration | Common Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of shares sold | shares		6,340,771
AbbVie Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of mile stone payments under second phase | Milestone	2
Initial milestone payment upon execution of amendment	$ 2,000
Increase in transaction price of performance obligation of second phase	$ 2,000
Cumulative catch-up adjustment to revenue, contract modification																$ 1,800
Remaining milestone achieved																	$ 2,500
Recognition of revenue															$ 2,200	$ 2,500
Current deferred revenue							$ 500								500
AbbVie Agreement | IBDCo
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront non-refundable payment						$ 2,000
Potential milestone payment															$ 16,500
Collaboration in research and development															54 months
Milestone payment					$ 2,000

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