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Selected Quarterly Data (unaudited) (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2019	Sep. 30, 2019	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Sep. 30, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2019	Dec. 31, 2018
Quarterly Financial Information Disclosure [Abstract]
Revenue	$ 1,231	$ 305	$ 350	$ 338	$ 111	$ 1,801	$ 254	$ 354	$ 2,224	$ 2,520
Operating expenses	14,710	14,443	13,445	14,035	12,819	13,335	15,606	11,990	56,633	53,750
Loss from operations	(13,479)	(14,138)	(13,095)	(13,697)	(12,708)	(11,534)	(15,352)	(11,636)	(54,409)	(51,230)
Net loss	$ (12,798)	$ (13,285)	$ (12,344)	$ (12,946)	$ (11,931)	$ (10,748)	$ (14,591)	$ (11,165)	$ (51,373)	$ (48,435)
Net loss per share - basic and diluted	$ (0.37)	$ (0.39)	$ (0.45)	$ (0.51)	$ (0.47)	$ (0.43)	$ (0.59)	$ (0.55)	$ (1.70)	$ (2.03)

X

- Definition

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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