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Leases - Additional Information (Detail) | 1 Months Ended | 12 Months Ended
--- | --- | ---
Apr. 30, 2021 | Jul. 31, 2017 USD ($) ft² | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2018 ft²
Lessee Lease Description [Line Items] |  |  |  |  |
Laboratory and office space to be leased | ft² |  | 41,346 |  |  |
Operating lease annual rent |  | $ 3,400,000 |  |  |
Term of lease |  | 10 years |  |  |
Tenant improvement investment |  | $ 2,900,000 |  |  |
Letter of credit |  | $ 1,000,000.0 |  |  |
Lessee, operating lease, existence of option to extend |  | true | true |  |
Renewal term of lease |  | 5 years |  |  |
Lessee, operating lease, existence of option to terminate |  | true |  |  |
Agreement expiration date |  |  |  |  | Dec. 31, 2022
Cash paid included in operating cash flows |  |  | $ 4,400,000 | $ 3,900,000 |
Master Services Agreement | Azzur Group, LLC |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |
Access and use of space under agreement | ft² |  |  |  |  | 700
Term of agreement |  |  |  |  | 44 months
New Agreement | Azzur Group, LLC |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |
Term of agreement | 20 months |  |  |  |
Agreement expiration date | Dec. 31, 2022 |  |  |  |
Maximum |  |  |  |  |
Lessee Lease Description [Line Items] |  |  |  |  |
Tenant improvement investment |  | $ 6,600,000 |  |  |

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- Definition Indicates (true false) whether lessee has option to extend operating lease. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 3 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980 + Details
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