XML 84 R63.htm IDEA: XBRL DOCUMENT v3.22.0.1

Leases - Additional Information (Detail)	1 Months Ended		12 Months Ended
	Apr. 30, 2021	Jul. 31, 2017 USD ($) ft²	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2018 ft²
Lessee Lease Description [Line Items]
Laboratory and office space to be leased | ft²		41,346
Operating lease annual rent		$ 3,400,000
Term of lease		10 years
Tenant improvement investment		$ 2,900,000
Letter of credit		$ 1,000,000.0
Lessee, operating lease, existence of option to extend		true	true
Renewal term of lease		5 years
Lessee, operating lease, existence of option to terminate		true
Agreement expiration date					Dec. 31, 2022
Cash paid included in operating cash flows			$ 4,400,000	$ 3,900,000
Master Services Agreement | Azzur Group, LLC
Lessee Lease Description [Line Items]
Access and use of space under agreement | ft²					700
Term of agreement					44 months
New Agreement | Azzur Group, LLC
Lessee Lease Description [Line Items]
Term of agreement	20 months
Agreement expiration date	Dec. 31, 2022
Maximum
Lessee Lease Description [Line Items]
Tenant improvement investment		$ 6,600,000

X

- Definition

Access and Use of space under agreement.

+ References

No definition available.

+ Details

Name:	sybx_AccessAndUseOfSpaceUnderAgreement
Namespace Prefix:	sybx_
Data Type:	dtr-types:areaItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Agreement expiration date.

+ References

No definition available.

+ Details

Name:	sybx_AgreementExpirationDate
Namespace Prefix:	sybx_
Data Type:	xbrli:dateItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Operating leases rent expense annual rental payments.

+ References

No definition available.

+ Details

Name:	sybx_OperatingLeasesRentExpenseAnnualRentalPayments
Namespace Prefix:	sybx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Rentable Space Under Lease Agreement

+ References

No definition available.

+ Details

Name:	sybx_RentableSpaceUnderLeaseAgreement
Namespace Prefix:	sybx_
Data Type:	dtr-types:areaItemType
Balance Type:	na
Period Type:	duration

X

- Definition

The amount the lessee agrees to invest into a tenant improvement of a leased property.

+ References

No definition available.

+ Details

Name:	sybx_TenantImprovementInvestmentObligation
Namespace Prefix:	sybx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Term of agreement.

+ References

No definition available.

+ Details

Name:	sybx_TermOfAgreement
Namespace Prefix:	sybx_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_LesseeLeaseDescriptionLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Indicates (true false) whether lessee has option to extend operating lease.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseExistenceOfOptionToExtend
Namespace Prefix:	us-gaap_
Data Type:	xbrli:booleanItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Indicates (true false) whether lessee has option to terminate operating lease.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseExistenceOfOptionToTerminate
Namespace Prefix:	us-gaap_
Data Type:	xbrli:booleanItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseRenewalTerm
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

+ References

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 3
-Subparagraph (a)(3)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980

+ Details

Name:	us-gaap_LesseeOperatingLeaseTermOfContract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.19(b),22(b))
-URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

+ Details

Name:	us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Amount of cash outflow from operating lease, excluding payments to bring another asset to condition and location necessary for its intended use.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 45
-Paragraph 5
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=123391704&loc=SL77918643-209977

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 842
-SubTopic 20
-Section 50
-Paragraph 4
-Subparagraph (g)(1)
-URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980

+ Details

Name:	us-gaap_OperatingLeasePayments
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

X

- Details

Name:	us-gaap_TypeOfArrangementAxis=sybx_MasterContractServicesAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	dei_LegalEntityAxis=sybx_AzzurGroupLimitedLiabilityCompanyMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	us-gaap_TypeOfArrangementAxis=sybx_NewAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	srt_RangeAxis=srt_MaximumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: