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Segment Information - Summary of Research and Development, General and Administrative Expenses, and Restructuring Charges are Significant Segment Expenses (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Segment Reporting Information [Line Items]
Research and development	$ 8	$ (713)	$ 16	$ 9,164
General and administrative	818	1,165	2,454	5,228
Restructuring and other charges	165	296	196	24,790
Clinical research and external costs
Segment Reporting Information [Line Items]
Research and development	8	(852)	23	4,062
Restructuring and other charges	0	20	(17)	322
Facility and all other costs
Segment Reporting Information [Line Items]
Research and development	0	114	0	3,136
General and administrative	54	35	170	787
Restructuring and other charges	0	35	(80)	15,537
Compensation and benefits
Segment Reporting Information [Line Items]
Research and development	0	25	(7)	1,966
General and administrative	139	342	433	1,603
Restructuring and other charges	58	221	167	8,245
Consulting and professional services
Segment Reporting Information [Line Items]
General and administrative	625	788	1,851	2,838
Restructuring and other charges	$ 107	$ 20	$ 126	$ 686

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- Definition

The aggregate total of expenses of managing and administering the affairs of an entity, including affiliates of the reporting entity, which are not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

+ References

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Amount of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation.

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