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Statements of Cash Flows - USD ($) | 6 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Jun. 30, 2015 | Jun. 30, 2014
Cash flows from operating activities |  |  |  |
Net loss | $ (5,608,568) | $ (3,725,772) | $ (7,723,404) | $ (5,578,690)
Stock-based compensation expense | 250,887 | 477,660 | 1,017,938 | 499,690
Depreciation, amortization and accretion | 242,427 | 49,164 | 118,202 | 97,476
Amoritzation of debt issuance costs | 147,805 | 0 |  |
Derivative expense | 78,038 | 0 |  |
Amortization of prepaid research and development - related party | 60,991 | 60,992 | 121,984 | 35,579
Deferred taxes | 0 | (23,910) | (23,910) | (813,697)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |
(Increase) in accounts receivable | (131,408) | (6,906) | (157,058) | 0
(Increase) in inventory | (613,673) | (10,453) | (39,442) | 0
(Increase) decrease in prepaid expenses, other | (370,656) | 485,889 | 150,434 | (497,322)
(Increase) in prepaid research and development - related party | 0 | (150,000) | (150,000) | (465,000)
(Decrease) in accounts payable and accrued liabilities | (126,781) | (298,677) |  |
Increase in accounts payable | 38,451 | (561,059) | 547,314 | 421,870
Increase in accrued compensation | 296,081 | 94,247 | 196,503 | 0
(Decrease) increase in interest payable to Ampio | 161,988 | 74,936 | (46,002) | 46,002
(Decrease) in payable to Ampio |  |  | (561,059) | 561,059
Increase in deferred rent | 10,245 | 0 |  |
(Decrease) increase in deferred revenue | (42,857) | (42,858) | (85,714) | 191,071
Net cash used in operating activities | (5,607,030) | (3,576,747) | (6,634,214) | (5,501,962)
Cash flows used in investing activities |  |  |  |
Deposits | 1,998 | (1,998) | (4,886) | 0
Purchase of ProstaScint Business | (540,000) | 0 | (1,000,000) | 0
Purchases of fixed assets | (125,161) | 0 | 0 | (9,298)
Net cash used in investing activities | (663,163) | (1,998) | (1,004,886) | (9,298)
Cash flows from financing activities |  |  |  |
Ampio stock subscription payment | 5,000,000 | 0 | 5,000,000 | 0
Proceeds from convertible promissory notes, net | 5,175,000 | 0 | 7,400,000 | 4,600,000
Luoxis option payout pursuant to the merger |  |  | (27,476) | 0
Liabilities paid out pursuant to the merger |  |  | (20,013) | 0
Contribution from Ampio | 0 | 1,100,000 | 0 | 637,210
Debt issuance costs (Note 8) | (298,322) |  |  |
Net cash provided by financing activities | 9,876,678 | 1,100,000 | 12,352,511 | 5,237,210
Net change in cash and cash equivalents | 3,606,485 | (2,478,745) | 4,713,411 | (274,050)
Cash and cash equivalents at beginning of period | 7,353,061 | 2,639,650 | 2,639,650 | 2,913,700
Cash and cash equivalents at end of period | 10,959,546 | 160,905 | 7,353,061 | 2,639,650
Non-cash transactions: |  |  |  |
Ampio stock subscription |  |  | 5,000,000 | 0
Ampio unpaid debt converted to stock, received prior to 2015 |  |  | 4,600,000 | 0
Contingent consideration related to the ProstaScint purchase |  |  | 664,000 | 0
Issuance of common stock in exchange for Vyrix acquired assets |  |  | 0 | 6,803,356
Related party research and development liability included in prepaid research and development - related party |  |  | $ 0 | $ 150,000
Warrant derivative liability related to the issuance of the convertible promissory notes (Note 8) | 102,931 | 0 |  |
Primsol business purchase included in primsol payable, $1,250,000 less future accretion of $173,000 | 1,077,000 | 0 |  |
Fixed asset purchases included in accounts payable | $ 7,708 | $ 0 |  |

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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Net Income -URI http://asc.fasb.org/extlink&oid=51831255 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04.19) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.18) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04.22) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 7: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Other Comprehensive Income -URI http://asc.fasb.org/extlink&oid=51831270 Reference 8: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 19 -Article 5 Reference 9: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 04 -Paragraph 20 -Article 9 + Details
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- Definition The cash outflow paid to third parties in connection with debt origination, which will be amortized over the remaining maturity period of the associated long-term debt. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3291-108585 + Details
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- Definition The distributions of earnings to an entity that is affiliated with the reporting entity by means of direct or indirect ownership. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3291-108585 + Details
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- Definition The cash outflow for financing costs associated with business combinations. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3291-108585 + Details
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- Definition The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3213-108585 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3213-108585 + Details
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- Definition The cash inflow associated with the amount received by a corporation from a shareholder during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3255-108585 + Details
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- Definition The cash inflow from parent as a source of financing that is recorded as additional paid in capital. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3255-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 + Details
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- Definition The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Financing Activities -URI http://asc.fasb.org/extlink&oid=6513228 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3255-108585 + Details
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