<SEC-DOCUMENT>0001144204-16-129428-index.html : 20161025
<SEC-HEADER>0001144204-16-129428.hdr.sgml : 20161025
<ACCEPTANCE-DATETIME>20161025171457
ACCESSION NUMBER:		0001144204-16-129428
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		12
FILED AS OF DATE:		20161025
DATE AS OF CHANGE:		20161025

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AYTU BIOSCIENCE, INC
		CENTRAL INDEX KEY:			0001385818
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				470883144
		STATE OF INCORPORATION:			CO
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-213738
		FILM NUMBER:		161951010

	BUSINESS ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 200
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112
		BUSINESS PHONE:		(720) 437-6580

	MAIL ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 200
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC.
		DATE OF NAME CHANGE:	20150609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Rosewind CORP
		DATE OF NAME CHANGE:	20070110
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>v450798_s1a.htm
<DESCRIPTION>S-1/A
<TEXT>
Document 1 - file: v450798_s1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.6
<SEQUENCE>2
<FILENAME>v450798_ex4-6.htm
<DESCRIPTION>EXHIBIT 4.6
<TEXT>
Document 2 - file: v450798_ex4-6.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>v450214_ex23x1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 3 - file: v450214_ex23x1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>line.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: line.gif

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>spacer.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: spacer.gif

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>logo_aytu-bioscience.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: logo_aytu-bioscience.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>v449009_ifc.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: v449009_ifc.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>v449009_chrt-org.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: v449009_chrt-org.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>v449009_img-testnasal.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: v449009_img-testnasal.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>v449009_chrt-line.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: v449009_chrt-line.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>v449009_img1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: v449009_img1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>v449009_img2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: v449009_img2.jpg

</DOCUMENT>
</SEC-DOCUMENT>