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v3.8.0.1

Consolidated Statements of Cash Flows (Unaudited) - USD ($) | 6 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2017 | Dec. 31, 2016 | Jun. 30, 2017 | Jun. 30, 2016
Cash flows from operating activities |  |  |  |
Net loss | $ (7,917,720) | $ (10,541,576) | $ (22,508,304) | $ (28,180,084)
Adjustments to reconcile net loss to cash provided by (used in) operating activities |  |  |  |
Depreciation, amortization and accretion | 1,315,063 | 1,722,965 | 4,364,680 | 874,789
Asset impairment |  |  | 1,265,125 | 7,500,000
Stock-based compensation expense | 275,688 | 1,425,133 | 2,502,092 | 902,946
Issuance of restricted stock | 103,635 | 156,814 | 724,613 |
Amortization of debt issuance costs |  |  |  | 182,759
Amortization of beneficial conversion feature |  |  |  | 4,943,073
Noncash interest expense |  |  |  | 221,024
Derivative (income) | (817,785) | (196,148) | (212,809) | 12,572
Amortization of prepaid research and development - related party (Note 9) |  | 60,992 | 335,454 | 121,983
Unrealized (gain) on investment |  | (230,936) | 61,519 | 971,629
Common stock issued to executives |  |  | 509,996 |
Compensation through issuance of stock |  | 509,996 |  |
Issuance of warrants to initial investors |  | 596,434 | 596,434 |
Gain on sale of asset |  |  | (428,374) |
Warrant amendment |  |  | 1,507 |
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |
(Increase) in accounts receivable | (849,397) | (419,966) | (355,031) | (5,369)
(Increase) decrease in inventory | (67,585) | 85,741 | 195,427 | (485,265)
(Increase) in prepaid expenses and other | (454,595) | (221,015) | (95,202) | 155,330
Increase (decrease) in accounts payable and other | 1,124,558 | (195,836) | 493,217 | 698,237
(Decrease) in accrued liabilities | (524,905) | (238,395) | (414,570) | 925,232
Increase (decrease) in accrued compensation | 497,586 | (681,432) | (861,226) | 1,004,427
(Decrease) in deferred rent | (3,337) | (1,350) | (4,200) | 10,875
(Decrease) in deferred revenue |  |  |  | (511,607)
Net cash used in operating activities | (7,318,794) | (8,168,579) | (13,829,652) | (10,657,449)
Cash flows used in investing activities |  |  |  |
Purchases of property and equipment | (12,195) | (44,876) | (111,608) | (252,932)
Installment payment for Natesto asset |  | (2,000,000) | (6,000,000) | (2,000,000)
Investment in Acerus |  |  | 1,071,707 | (2,012,991)
Sale of investment in Acerus cost |  |  | (91,864) |
Sales of Primsol assets |  |  | 1,750,000 |
Installment payment for Primsol asset |  | (750,000) | (750,000) | (1,040,000)
Cash proceed from Nuelle |  |  | 613,309 |
Cost related to Nuelle acquisition |  |  | (16,082) |
Deposits |  |  |  | 1,998
Net cash used in investing activities | (12,195) | (2,794,876) | (3,534,538) | (5,303,925)
Cash flows from financing activities |  |  |  |
Issuance of common stock to Lincoln Park Capital |  | 631,481 | 739,857 |
Costs related to sale of common stock |  | (24,247) | (90,924) |
Warrant tender offer |  |  | 2,243,282 |
Warrant tender offer cost |  |  | (312,159) |
Proceeds from convertible promissory notes, net (Note 8) |  |  |  | 5,175,000
Debt issuance costs (Note 8) |  |  |  | (298,322)
Costs related to the conversion of the convertible promissory notes to equity |  |  |  | (29,754)
Ampio stock subscription payment |  |  |  | 5,000,000
Registered offering |  | 8,602,500 | 8,602,499 | 7,520,493
Registered offering costs |  | (997,865) | (997,865) | (904,914)
Over-allotment warrants purchased by placement agents |  | 2,852 | 2,852 |
Issuance of preferred, common stock and warrants | 11,839,995 |  |  |
Sale of stock subscription |  |  |  | 200,000
Net cash provided by financing activities | 10,437,164 | 8,214,721 | 10,187,542 | 16,662,503
Issuance costs related to preferred, common stock and warrants | (1,402,831) |  |  |
Net change in cash, cash equivalents and restricted cash | 3,106,175 | (2,748,734) | (7,176,648) | 701,129
Cash, cash equivalents and restricted cash at beginning of period | 877,542 | 8,054,190 | 8,054,190 | 7,353,061
Cash, cash equivalents and restricted cash at end of period | 3,983,717 | 5,305,456 | 877,542 | 8,054,190
Non-cash transactions: |  |  |  |
Warrants issued to investors and underwriters (see Note 5) | 4,117,997 |  |  |
Revenue share payment to Jazz | 7,385 |  |  |
Earn-out payment to Nuelle Shareholders | 250,000 |  |  |
Issuance of common stock to Nuelle share holders |  |  | 1,837,500 |
Fixed assets included in accounts payable | 62,512 | 61,241 | 10,789 |
Warrants issued in connection with the equity financing to the placement agents |  | $ 292,630 | 292,630 |
Warrants amended in connection with warrant tender offer |  |  | 63,182 |
Warrant derivative liability related to the issuance of the convertible promissory notes (Note 8) |  |  |  | 102,931
Primsol asset purchase included in Primsol payable, $1,250,000 less future accretion of $173,000 |  |  |  | 1,077,000
Conversion of convertible promissory notes and interest of $221,000 to common stock |  |  |  | 5,396,024
Natesto asset purchase included in Natesto payable, $6,000,000 less future accretion of $620,325 |  |  |  | 5,379,675
Warrant derivative liability related to the issuance of the registered offering placement agent warrants (Note 8) |  |  |  | 297,317
Reclassification of liability based warrants to equity presentation related to the convertible promissory notes |  |  |  | 136,828
Beneficial conversion feature related to convertible promissory notes |  |  |  | 4,943,073
Debt issuance costs related to notes that converted to equity |  |  |  | $ (218,494)

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- Definition The increase (decrease) during the reporting period, excluding the portion taken into income, in the liability reflecting revenue yet to be earned for which cash or other forms of consideration was received or recorded as a receivable. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition The increase (decrease) during the reporting period in the aggregate value of all inventory held by the reporting entity, associated with underlying transactions that are classified as operating activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition The increase (decrease) during the reporting period in the amount of outstanding money paid in advance for goods or services that bring economic benefits for future periods. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Amount of increase (decrease) of consideration paid in advance for rent that provides economic benefits in future periods. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Fair value of share-based compensation granted to nonemployees as payment for services rendered or acknowledged claims. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Amount of cash inflow (outflow) of financing activities, excluding discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3574-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3521-108585 + Details
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- Definition Amount of cash inflow (outflow) of investing activities, excluding discontinued operations. Investing activity cash flows include making and collecting loans and acquiring and disposing of debt or equity instruments and property, plant, and equipment and other productive assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3574-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3521-108585 + Details
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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3536-108585 + Details
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- Definition The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-04(22)) -URI http://asc.fasb.org/extlink&oid=6879574&loc=d3e536633-122882 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 225 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-04(18)) -URI http://asc.fasb.org/extlink&oid=6879464&loc=d3e573970-122913 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03(20)) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 + Details
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- Definition Amount of expense or loss included in net income that result in no cash flow, classified as other. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition The cash outflow associated with other payments to acquire businesses including deposit on pending acquisitions and preacquisition costs. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The net amount paid (received) by the reporting entity through acquisition or sale and maturities of long-term investments which qualify for treatment as an investing activity based on management's intention and intended by management to be liquidated, if necessary, beyond the current operating cycle. Includes cash flows from securities classified as trading securities that were acquired for reasons other than sale in the long-term. + References No definition available. + Details
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- Definition The cash outflow paid to third parties in connection with debt origination, which will be amortized over the remaining maturity period of the associated long-term debt. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The cash outflow for cost incurred in the modification of term of existing debt agreement in order for the entity to achieve some advantage. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The cash outflow for cost incurred directly with the issuance of an equity security. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3291-108585 + Details
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- Definition The cash outflow for securities or other assets acquired, which qualify for treatment as an investing activity and are to be liquidated, if necessary, beyond the current operating cycle. Includes cash flows from securities classified as trading securities that were acquired for reasons other than sale in the long-term. + References No definition available. + Details
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- Definition Amount of cash outflow for the purchase of or improvements to tangible or intangible assets, used to produce goods or deliver services, classified as other. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The cash outflow associated with the acquisition of long-lived, physical assets that are used in the normal conduct of business to produce goods and services and not intended for resale; includes cash outflows to pay for construction of self-constructed assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3213-108585 + Details
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- Definition The cash inflow from parent as a source of financing that is recorded as additional paid in capital. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from the issuance of a long-term debt instrument which can be exchanged for a specified amount of another security, typically the entity's common stock, at the option of the issuer or the holder. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from the additional capital contribution to the entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from issuance of rights to purchase common shares at predetermined price (usually issued together with corporate debt). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 14 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3255-108585 + Details
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- Definition Amount of cash inflow from the sale of tangible or intangible assets used to produce goods or deliver services, classified as other. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3179-108585 + Details
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- Definition The noncash expense that represents the cost of restricted stock or unit distributed to employees as compensation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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- Definition Amount of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 5.P.3) -URI http://asc.fasb.org/extlink&oid=27011515&loc=d3e140864-122747 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6394359&loc=d3e17939-110869 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB Topic 5.P.4(b)) -URI http://asc.fasb.org/extlink&oid=27011515&loc=d3e140904-122747 + Details
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