    <SEC-DOCUMENT>0001213900-18-006001-index.html : 20180514
    <SEC-HEADER>0001213900-18-006001.hdr.sgml : 20180514
    <ACCEPTANCE-DATETIME>20180511192346
    ACCESSION NUMBER:		0001213900-18-006001
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		7
    FILED AS OF DATE:		20180514
    DATE AS OF CHANGE:		20180511
    EFFECTIVENESS DATE:		20180514

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			AYTU BIOSCIENCE, INC
    		CENTRAL INDEX KEY:			0001385818
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				470883144
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			0630

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38247
    		FILM NUMBER:		18828397

    	BUSINESS ADDRESS:
    		STREET 1:		373 INVERNESS PARKWAY
    		STREET 2:		SUITE 206
    		CITY:			ENGLEWOOD
    		STATE:			CO
    		ZIP:			80112
    		BUSINESS PHONE:		(720) 437-6580

    	MAIL ADDRESS:
    		STREET 1:		373 INVERNESS PARKWAY
    		STREET 2:		SUITE 206
    		CITY:			ENGLEWOOD
    		STATE:			CO
    		ZIP:			80112

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC.
    		DATE OF NAME CHANGE:	20150609

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Rosewind CORP
    		DATE OF NAME CHANGE:	20070110
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>defa14a0518_aytubioscience.htm
    <DESCRIPTION>DEFINITIVE ADDITIONAL MATERIALS
    <TEXT>
    Document 1 - file: defa14a0518_aytubioscience.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>slide_1.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: slide_1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>slide_2.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: slide_2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>slide_3.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: slide_3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>slide_4.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: slide_4.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>slide_5.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: slide_5.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>slide_6.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: slide_6.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>