<SEC-DOCUMENT>0001213900-20-014381-index.html : 20200608
<SEC-HEADER>0001213900-20-014381.hdr.sgml : 20200608
<ACCEPTANCE-DATETIME>20200608161529
ACCESSION NUMBER:		0001213900-20-014381
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		11
FILED AS OF DATE:		20200608
DATE AS OF CHANGE:		20200608

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AYTU BIOSCIENCE, INC
		CENTRAL INDEX KEY:			0001385818
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				470883144
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0630

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-239010
		FILM NUMBER:		20949283

	BUSINESS ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112
		BUSINESS PHONE:		(720) 437-6580

	MAIL ADDRESS:	
		STREET 1:		373 INVERNESS PARKWAY
		STREET 2:		SUITE 206
		CITY:			ENGLEWOOD
		STATE:			CO
		ZIP:			80112

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AYTU BIOSCIENCE, INC.
		DATE OF NAME CHANGE:	20150609

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Rosewind CORP
		DATE OF NAME CHANGE:	20070110
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>ea122645-s3_aytubioscience.htm
<DESCRIPTION>REGISTRATION STATEMENT
<TEXT>
Document 1 - file: ea122645-s3_aytubioscience.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.2
<SEQUENCE>2
<FILENAME>ea122645ex1-2_aytubio.htm
<DESCRIPTION>OPEN MARKET SALE AGREEMENTSM, DATED JUNE 5, 2020, BY AND BETWEEN AYTU BIOSCIENCE, INC. AND JEFFERIES
<TEXT>
Document 2 - file: ea122645ex1-2_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.14
<SEQUENCE>3
<FILENAME>ea122645ex4-14_aytubio.htm
<DESCRIPTION>FORM OF INDENTURE
<TEXT>
Document 3 - file: ea122645ex4-14_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>4
<FILENAME>ea122645ex5-1_aytubio.htm
<DESCRIPTION>OPINION OF DORSEY & WHITNEY LLP
<TEXT>
Document 4 - file: ea122645ex5-1_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.2
<SEQUENCE>5
<FILENAME>ea122645ex5-2_aytubio.htm
<DESCRIPTION>OPINION OF DORSEY & WHITNEY LLP
<TEXT>
Document 5 - file: ea122645ex5-2_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>6
<FILENAME>ea122645ex23-2_aytubio.htm
<DESCRIPTION>CONSENT OF PLANTE & MORAN, PLLC RELATING TO AYTU'S FINANCIAL STATEMENTS
<TEXT>
Document 6 - file: ea122645ex23-2_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>7
<FILENAME>ea122645ex23-3_aytubio.htm
<DESCRIPTION>CONSENT OF HALL & COMPANY RELATING TO INNOVUS' FINANCIAL STATEMENTS.
<TEXT>
Document 7 - file: ea122645ex23-3_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.4
<SEQUENCE>8
<FILENAME>ea122645ex23-4_aytubio.htm
<DESCRIPTION>CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS OF THE ABBREVIATED FINANCIAL STATEMENTS OF THE PEDIATRICS PRODUCT PORTFOLIO OF CERECOR INC.
<TEXT>
Document 8 - file: ea122645ex23-4_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.5
<SEQUENCE>9
<FILENAME>ea122645ex23-5_aytubio.htm
<DESCRIPTION>CONSENT OF EKS&H LLLP, PREDECESSOR INDEPENDENT PUBLIC ACCOUNTING FIRM, RELATING TO AYTU'S FINANCIAL STATEMENTS
<TEXT>
Document 9 - file: ea122645ex23-5_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>10
<FILENAME>ea122645ex99-1_aytubio.htm
<DESCRIPTION>UNAUDITED PRO FORMA CONDENSED COMBINED STATEMENT OF OPERATIONS FOR THE YEAR ENDED JUNE 30, 2019 AND NINE MONTHS ENDED MARCH 31, 2020
<TEXT>
Document 10 - file: ea122645ex99-1_aytubio.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>image_001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: image_001.jpg

</DOCUMENT>
</SEC-DOCUMENT>